To hydrophilic, polyfunctional spherical microparticles of predetermined diameter, produced by copolymerization of acrylic monomers, we covalently bound human thyroglobulin. The thyroglobulin-microsphere conjugate was agglutinated, in the presence of antimouse immunoglobulins antiserum, by four monoclonal antibodies, each recognizing a different antigenic domain on the thyroglobulin molecule. T...

Abstract Background The reported incidence of postlobectomy hypothyroidism is quite different among studies with an average 22%. Many risk factors predict the development in patient undergoing thyroid lobectomy. Aim aim this study was to assess predictors after Methods A retrospective observational conducted at Faiha Specialized Diabetes, Endocrine, and Metabolism Center Zain Alabdeen Teaching ...

PURPOSE It has been reported that antithroglobulin (anti-TG) antibody is increased in the sera of both children with transient congenital hypothyroidism and their mothers. And transplacental transport of thyroid autoantibody was proposed as the pathogenesis of transient congenital hypothyroidism. However this is not known in nontransient congenital hypothyroidism. This study was done to see cha...

BACKGROUND Even though the presence of antithyroglobulin antibodies (TgAbs) represents a significant problem in the follow-up of patients with differentiated thyroid cancer (DTC), the current guidelines on the management of DTC that have been published in recent years contain no text concerning the methods to be used for detecting such antibody-related interference in thyroglobulin (Tg) measure...

Abstract Introduction Thyroid is an endocrine gland. It produce T3 and T4 hormones through a series of enzymatic actions. These regulate body metabolism physiology. Immune disorders in this gland can cause hypo/hyperthyroidism. Objective The study aimed to assess antithyroid antibodies patients with benign thyroid masses the effect total thyroidectomy on titres. Patients Methods This retrospect...

Previous studies indicate that 25-45% of chronic urticaria patients have an autoimmune etiology. Autologous serum skin test (ASST) and autologous plasma skin test (APST) are simple tests for diagnosing chronic autoimmune urticaria (CAU). However, there are still some questions about the specificity of these tests. This study consisted of 50 patients with chronic spontaneous urticaria (CSU) and ...

Objective To compare the short- and long-term outcomes of adjuvant therapy with radioactive iodine (RAI) preceded by the administration of recombinant human TSH (rhTSH) versus thyroid hormone withdrawal (THW) in patients with papillary thyroid carcinoma and clinically apparent lymph node metastases not limited to the central neck compartment (cN1b). Subjects and methods The sample consisted o...