BACKGROUND The aim of this study was to extend previous in vitro observations regarding the effects of multiple actuations of aerosols into spacer devices, delayed inhalation, and antistatic treatment of spacer devices on the amount of drug delivered for inhalation. An in vivo study of lung bioavailability of salbutamol from a large volume (Volumatic) spacer was conducted. METHODS Ten healthy...

Topanol A is a phenolic antioxidant additive, which is used in storage tanks for jet fuels produced in the petroleum refineries throughout the country. Topanol A mostly consists of 2,6-di-t-butylphenol. The conventional methods for the preparation of this compound involve ortho-alkylation of phenol using 2-methylpropene (isobutylene) as the alkylating agent. The compound has been prepared by or...

Biocomposites with unique functionalities for tailored applications are promising products for a sustainable future. In this work, a process concept of forming functional composites by combining of high-density polyethylene, carbon black, and magnetic lignocellulosic particles (wood flour) was demonstrated. The impacts of process parameters on morphologies, crystalline phase, and magnetic inten...

Droplet microfluidics can form and process millions of picoliter droplets with speed and ease, allowing the execution of huge numbers of biological reactions for high-throughput studies. However, at the conclusion of most experiments, the emulsions must be broken to recover and analyze their contents. This is usually achieved with demulsifiers, like perfluorooctanol and chloroform, which can in...

Introduction Conclusions References