Antiphospholipid syndrome can mimic many diseases, one of which is multiple sclerosis. The article presents the main aspects differential diagnosis antiphospholipid and sclerosis, as well its own clinical case.

Blood samples from 65 patients with primary Sjögren's syndrome were evaluated for the presence of antiphospholipid antibodies. Increased levels of antiphospholipid antibodies were found in 13 of 65 (20%) of patients. These antiphospholipid antibodies were predominantly of the IgA isotype, in contrast with the IgG isotype antiphospholipid antibodies found in patients with systemic lupus erythema...

Antiphospholipid syndrome is a systemic autoimmune disease with thrombotic tendency. Consensus guidelines for pregnancy with antiphospholipid syndrome recommend low-dose aspirin combined with unfractionated or low-molecular-weight heparin because antiphospholipid syndrome causes habitual abortion. We report a 36-year-old pregnant woman diagnosed with antiphospholipid syndrome receiving anticoag...

Background. Antiphospholipid syndrome (APS) characterized by thrombosis and abortus may rarely cause primary adrenal failure. Case Presentations. A 34-year-old male presented with hypotension, hypoglycemia, hyperpigmentation on his skin and oral mucosa, scars on both legs, and loss of consciousness. In laboratory examinations, hyponatremia (135 mmol/L), hyperpotassemia (6 mmol/L), and thrombocy...

Antiphospholipid syndrome is an acquired autoimmune thrombophilia characterized by the development of recurrent vascular thrombosis any caliber and type or obstetric pathology mandatory identification persistently positive antiphospholipid antibodies. The main drug in treatment patients with warfarin. role direct-acting oral anticoagulants remains controversial. article discusses modern data on...

AIM We audited indications and outcomes of antiphospholipid syndrome (APS) screening in the pregnant population at our centre. METHOD Prospective and observational. All APS test results returned were audited for validity of indication and subsequent outcome. RESULT 24 of a total of 146 (16%) of requests for the antiphospholipid antibodies and lupus anticoagulant were not indicated. Two posi...

Sir, The occurrence of antiphospholipid syndrome in childhood onset SLE has been repor ted var iably.1,2 We compared retrospectively, the occurrence of antiphospholipid syndrome in both childhood and adult onset SLE seen in our unit over one year period. Of the 76 patients, 18 (24%) were of childhood onset variety. This is comparable to that available in literature.3 Antiphospholipid syndrome w...

Catastrophic antiphospholipid syndrome (CAPS) is an acutely devastating situation characterized by widespread thrombotic microangiopathy in the presence of elevated titers of antiphospholipid antibodies. We describe a 57-year old woman who underwent liver transplantation for primary sclerosing cholangitis and developed this malignant variant of the antiphospholipid syndrome.

Antiphospholipid syndrome is an autoimmune disorder defined as association of vascular thrombosis and/or pregnancy complications with presence of antiphospholipid antibodies (lupus anticoagulant, anticardiolipin and anti-β2 glycoprotein I). It is the most common cause of acquired thrombophilia, and can occur as an independent entity or in relation with other diseases, especially systemic lupus ...

131 ISSN 1758-4272 10.2217/IJR.11.81 © 2012 Future Medicine Ltd Int. J. Clin. Rheumatol. (2012) 7(2), 131–134 “Renal pathologists should be aware of the histologic characteristics of antiphospholipid syndrome-associated nephropathy when they examine kidney biopsies of systemic lupus erythematosus patients, especially those with positive antiphospholipid antibodies.” Antiphospholipid syndrome-as...