نتایج جستجو برای: antiparasitic activity
تعداد نتایج: 1135284 فیلتر نتایج به سال:
With the increase of neglected diseases such as leishmaniasis and Chagas disease, there wasa need for the search for new therapeutic alternatives that reduce the harm caused by medicineavailable for treatment. Thus, this study was performed to investigate the antiparasitic activityof the essential oil from the fruits of Piper tuberculatum Jacq, against lines of Leishmaniabraziliensis (MHOM/CO/8...
With the increase of neglected diseases such as leishmaniasis and Chagas disease, there wasa need for the search for new therapeutic alternatives that reduce the harm caused by medicineavailable for treatment. Thus, this study was performed to investigate the antiparasitic activityof the essential oil from the fruits of Piper tuberculatum Jacq, against lines of Leishmaniabraziliensis (MHOM/CO/8...
The Latin American plant Tabernaemontana longipes was studied in this work as a potential source of antiparasitic agents. The chloroform extract of T. longipes leaves was separated into several fractions, and tested for antitrypanosomal activity. One of the fractions displayed significant growth inhibitory activity against Trypanosoma brucei. The active principle in the fraction was isolated, p...
This study evaluated the anti-Toxoplasma gondii potential of gold, silver, and platinum nanoparticles (NPs). Inorganic NPs (0.01-1,000 µg/mL) were screened for antiparasitic activity. The NPs caused >90% inhibition of T. gondii growth with EC50 values of ≤7, ≤1, and ≤100 µg/mL for gold, silver, and platinum NPs, respectively. The NPs showed no host cell cytotoxicity at the effective anti-T. gon...
Nitazoxanide is a new thiazolide antiparasitic agent that shows excellent in vitro activity against a wide variety of protozoa and helminths. It is given by the oral route with good bioavailability and is well tolerated, with primarily mild gastrointestinal side effects. At present, there are no documented drug-drug interactions. Nitazoxanide has been licensed for the treatment of Giardia intes...
UNLABELLED In screening for natural products with antiparasitic activity, an endophytic fungus, strain F2611, isolated from above-ground tissue of the tropical grass Paspalum conjugatum (Poaceae) in Panama, was chosen for bioactive principle elucidation. Cultivation on malt extract agar (MEA) followed by bioassay-guided chromatographic fractionation of the extract led to the isolation of the ne...
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