an efficient and simple one-pot approach for the synthesis of 3,4-dihydropyrimidin-2-(1h)-one derivatives using antimony trichloride (sbcl3) as a mild catalyst by means of three-component biginelli reaction between β-keto esters, aldehyde derivatives and urea/thiourea under thermal and solvent-free conditions with excellent yields and short reaction times is reported. this methodology offers se...

IN January 1932 work was started in the National Institute for Research in Dairying to investigate the variations in the vitamin content of typical English milk as determined by the season of the year and the nutritional condition of the cow. This work, which was planned to cover two complete years, and which will be described in detail later, is mainly concerned with the accumulation of data o...

THERE is still a great deal of uncertainty regarding the relative biological activities of vitamin A and carotene. The subject has been reviewed recently by Moore [1933], who has summarised the findings of various workers and has pointed out the very wide variations in the reported minimum doses of the two substances. On the basis of his own experiments in which he directly compared f-carotene ...

The numerous combinations of functional groups occurring in the steroid hormones render difficult the development of a specific test for individual compounds. However, reactions which reveal certain groupings are available and may be applied singly or in combination to elucidate the characteristics of pure steroids or of compounds in a mixture. The ketol side chain, located at carbon atom 17 in...