" stibacetin," which was the first aromatic compound of antimony to be used in the treatment of leishmaniasis, many aromatic compounds of antimony have been introduced. Von Heyden also introduced sodium meta-chloro-para-acetylamino stibinate, known as No. 471 or " stibosan," and an amine salt of p-amino-phenyl-stibinic acid known as No. 693 iboth of which proved to be very effective in the trea...

A series of antimony-doped Ba(8)Ga(16)Ge(30) clathrates was grown as large crystals from gallium flux. These compounds form in the cubic space group Pm(-)3n, with the unit cell parameter varying from 10.784(5) to 10.9008(6) A as the amount of GaSb substituting for germanium atoms in the framework is increased. It was found that more antimony than extra gallium was incorporated into the material...

1. Conditions were established for the reaction of retinal with phosphatidylethanolamine, phosphatidylserine, ethanolamine and serine in chloroform, ethanol or ethanol-water solutions to form retinylidene compounds, or Schiff bases. 2. The Schiff bases were reduced to retinyl compounds with sodium borohydride. 3. Absorption maxima and molar extinction coefficients were determined for the variou...

17 Antimony-based drugs are still the mainstay of chemotherapy against Leishmania infections in 18 many endemic countries. Efficacy of antimonials has been compromised by increasing numbers of 19 resistant infections, the basis of which is not fully understood and likely involves multiple factors. 20 By using a functional cloning strategy he have recently identified a novel antimony resistance ...

In their attempts to further this advance they were, however, very severely handicapped; from Germany they were entirely cut off, English chemists were otherwise occupied, and, probably the most important factor of all, commercial firms could not be persuaded to introduce new antimony compounds or even to put on the market antimony tartrates of a higher standard of purity than the usual commerc...

The use of antimony compounds, particularly potassium antimonyl tartrate (Tartar emetic), in Cryptococcosis has occasionally been mentioned in the literature,2"' but no experimental study of the therapeutic rationale of the use of antimonials in this infection has to our knowledge ever been under-taken. It did not seem that Tartar emetic was of any therapeutic value, but this should not reflect...

A pentavalent antimony compound (Sdt. 561, solustibosan, antimony-v-hexonate, containing 20 mg. of antimony per c.cm. of solution) , that made a stable solution and could be given intramuscularly, was first introduced b) Prof. H. Schmidt, the pioneer worker on pent*1' valent antimony compounds. Kikuth and Schmidt (1938) found that this compound possessed a marked curative action in the le*,' ma...

Two novel Sb(III) and Sb(V) peri-substituted acenaphthene phosphorus−antimony compounds were prepared. The compound, 1, was prepared via reacting the organolithium precursor with dichloro(p-tolyl)Stibine, 2 by chlorination of 1. Both 1 characterized multinuclear (1H, 13C 31P) NMR spectroscopy, their molecular structures resolved single-crystal X-ray diffraction. show a dative P−Sb interaction a...