نتایج جستجو برای: antifungal effect
تعداد نتایج: 1662710 فیلتر نتایج به سال:
introduction: microorganisms and microbial products are the main etiologic factors in pulp and periapical diseases. the present study aimed to compare the antifungal activity of two different sealers, ah-26 and mta fillapex against three strains of candida, 24, 48, 72 h and 7 days after mixing. methods and materials: the microorganisms used in this study were candidia albicans ( atcc 10231) , c...
Human peripheral blood polymorphonuclear leucocytes (PMN) were examined in vitro for antifungal activity against yeast cells of Paracoccidioides brasiliensis. The yeast cell of this fungus was resistant to killing by PMN. However, PMN exhibited a fungistatic effect on the fungal isolates employed in a long-term ( approximately 72 h) assay. Lysates of PMN did not show a fungistatic or fungicidal...
Calcineurin inhibitors may augment the effects of antifungal drugs in microbiological assays. We examined this interaction in a microbiological assay for posaconazole. No effect was observed. However, concurrent or recently discontinued treatment with other antifungal drugs caused false-positive results, emphasizing a limitation of microbiological assays for antifungal drug level measurement.
Background and Aim: Ear wax is the combination of different producing gland secretions. According to controversial ideas about the antifungal effects of ear cerumen and lack of any research around this matter in Iran, the present study performed on antifungal activity of cerumen from healthy people referred to Beheshti Hospital, Babol on some fungi. Materials and Methods: This experimental stu...
Sea cucumber is presented as potential marine source of antimicrobial compounds. The purpose of this study is to evaluate antifungal effects of sea cucumber, Holothuria leucospilota, extracts on Aspergillus niger and Candida albicans. Methanol and chloroform extracts of the body wall, gonad and intestine of sea cucumber, H. leucospilota, collected from Persian Gulf, were evaluated for their ant...
Background: Nystatin is a polyene with antifungal effect which is used in treatment of cutaneous and mucocutaneous candidiasis in diverse forms. Increasing its utilization in recent years has led to predominant increasing of resistances. Nowadays for increasing of antifungal effect and decreasing of resistance and side effects of drugs they are used in combination with each other. So w...
Background and Aim: Human cutaneous infections are caused by a homogeneous group of kreatinophilic fungi, called Dermatophytes. Such infections are accounted as a principle public health, at present. Microsporum gypseum a cause of baldness in Iran. Cases occur sporadically due to Microsporum gypseum in puppies and soil and is transmitted to humans. Since these pathogenic dermatophytes are eukar...
Background: Among important fungi associated with foods are Aspergillus spp., Penicillium spp., and Geotrichum spp. In this study, we evaluated antifungal effects of Essential Oils (EOs) of Zataria multiflora, Mentha pulegium, and Mentha piperita. Methods: Antifungal properties of EOs of M. piperita, M. pulegium, and Z. multiflora against Aspergillus spp., Penicillium spp., and Geotrichum ca...
BACKGROUND Plagiochin E (PLE) is an antifungal macrocyclic bis(bibenzyl) isolated from liverwort Marchantia polymorpha L. Its antifungal mechanism is unknown. To elucidate the mechanism of action, its effect on mitochondria function in Candida albicans was studied. METHODS We assayed the mitochondrial membrane potential (mtDeltapsi) using rhodamine 123, measured ATP level in mitochondria by H...
BACKGROUND AND OBJECTIVE Very little is known about the response rates to or appropriateness of treatment for patients with allergic fungal diseases of the lung. This study assessed the effect of antifungal therapy in patients with severe asthma with fungal sensitization (SAFS) and allergic bronchopulmonary aspergillosis (ABPA). METHODS A retrospective cohort study of 33 adult patients who fu...
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