the discovery of the antifertility activity of gossypol led scientists and researchers to the development of compounds with antifertility activity that can be used as male contraceptives. these studies resulted in discovery of the antifertility activity of several classes of compounds which have been reported in the literature. this article deals with the synthesis of four new analogues of pyri...

Alcoholic extract of Acacia leucophploea root was investigated to find out their antifertility activity. Antifertility activity was evaluated by estrus cycle study, genital organ weight and biochemical parameter. Alcoholic extract at 200 mg/kg dose increased proestrus phase significantly while estrus and metaestrus phases were decreased. At this dose weight of ovary also decreased and cholester...

The discovery of the antifertility activity of gossypol led scientists and researchers to the development of compounds with antifertility activity that can be used as male contraceptives. These studies resulted in discovery of the antifertility activity of several classes of compounds which have been reported in the literature. This article deals with the synthesis of four new analogues of pyri...

In recent year, there were various types of contraceptives developed having different mode of action. These contraceptives are prepared from natural as well as synthetic sources. These contraceptives worked by prevent the fusion of sperm into ovum, change female hormonal levels and spermicidal activity. Many compounds with different pharmacological activity have been evaluated in vitro for thei...

Introduction Metal complexes play an essential role in agriculture, pharmaceutical and industrial chemistry. Ligand, a metal surrounded by a cluster of ions or molecule, is used for preparation of complex compounds named as Schiff bases, which are condensation products of primary amines and aldehydes or ketones (RCH=NR′, where R & R′ represents alkyl and / or aryl substituents). This paper revi...

Medicinal plants play a key role in human life as they are helpful in curing several diseases. They not only support health by the pharmacological nature but also utilizable as contraceptive options. The present study reveals that the medicinal plants Melia azedarach and Dodonaea viscosa leaf extracts showing antifertility activity. The decreased sperm count and reproductive organ weights inclu...

Many antimalarial remedies are known for reproductive toxicity in male. Also, several plants to have antifertility action both sexes. The aim of this study is evaluate the effect ethanol extract Senna occidentalis (L.) Link Leguminosae leaf (EESO) on male parameters such as sperm count, motility, morphology and histology testes Wistar rats by employing standard procedures. (50% ethanol) was ora...

FTER parental exposure to mutagens and subsequent mating, adverse A genetic effects may manifest sequentially by preimplantation losses of fertilized ova and zygotes, early fetal deaths, and sterility and semisterility in F, progeny ( CATTANACH 1964; EPSTEIN et al. 1970a). Effects of ionizing irradiation of the male or of sperm in uitro on fertilization and subsequent development of the zygote ...

Evaluation of herbs for antifertility effects has been in progress worldwide for several decades to identify effective and safe substances for control of population explosion. Inspite of availability of internationally accepted guidelines for the assessment of reproductive toxicity/antifertility potential of test substances, many published articles, on critical review, seem to lack reproducibil...