nigella sativa (n. sativa), which belongs to the botanical family of ranunculaceae, is a widely used medicinal plant all over the world. n. sativa seeds and oil have been used in the treatment of different diseases. various studies on n. sativa have been carried out and a broad spectrum of its pharmacological actions have been established which include antioxidant, antidiabetic, anticancer, ant...

The direct oral anticoagulants (DOACs), which include dabigatran, rivaroxaban, apixaban, and edoxaban, can be given in fixed doses without routine coagulation monitoring. In clinical trials, the DOACs have been shown to be at least as effective as vitamin K antagonists (VKAs), such as warfarin, for stroke prevention in nonvalvular atrial fibrillation and for treatment of venous thromboembolism,...

Introduction: Rapid treatment of patients with anticholinergic toxicity in the Ernergcncy Department (ED) has remained problematic for many years. These patients are often agitated. uncooperative, and unable to provide a clear history. Physostigmine is a specific antidote for anticholinergic toxicity. yet its popularity has waned due to controversy surrounding its potential central nervo~is sys...