Problem statement: Dermatophytes have developed resistance to the existing antifungal antibiotics. As a part of our continuous search we had isolated, identified and characterized actinomycetes from the halophilic environment having antagonistic activity against the dermatophytes namely Trichophyton, Microsporum and Epidermophyton. Approach: Actinomycetes were isolated from the soil sample coll...

Dermatophytes are one of the major aetiologic agents cutaneous mycoses Senna occidentalis is among plants used in traditional herbal medicine treating fungal skin infections and it shown from literature to contain phytochemicals which attributed its antidermatophytic activity. This work aimed at determining Phytoconstituents activity leaves seeds crude extracts plant . The study a qualitative t...

CONTEXT Due to increase in the number of patients with impaired immunity, incidence of dermatophytoses has increased considerably. Antidermatophytic agents with anti-inflammatory and protease-inhibiting activities will help in restricting inflammatory response associated with dermatophytoses. AIMS The present study aims to evaluate antidermatophytic and protease-inhibiting activities of zerum...

This study examined whether the antidermatophytic activity of essential oils (EOs) can be used as an indicator for the discovery of active natural products against Leishmania amazonensis. The aerial parts of seven plants were hydrodistilled. Using broth microdilution techniques, the obtained EOs were tested against three strains of dermatophytes (Trichophyton mentagrophytes, Microsporum gypseum...

The present investigation reports the synthesis of a phenylalanine-rich N-methylated cyclopeptide, cordyheptapeptide A (8), previously isolated from the insect pathogenic fungus Cordyceps sp. BCC 1788, accomplished through the coupling of N-methylated tetrapeptide and tripeptide fragments followed by cyclization of the linear heptapeptide unit. Structure elucidation of the newly synthesized cyc...