snake venoms contain a rich variety of factors which affect blood coagulation. there have been few reports on the anticoagulant activity of the venom of different cobras, but no such observations have been made on the iranian cobra, although a procoagulant factor has been described. in this study an anticoagulant factor has been purified from the venom of naja naja oxiana using gel filtration f...

A patient with a circulating lupus anticoagulant in the absence of systemic lupus erythematosus developed recurrent deep venous thromboses and pulmonary emboli. Pulmonary emboli recurred despite prolonged oral anticoagulant therapy and resulted in fatal pulmonary arterial hypertension. Extended anticoagulant therapy alone may not prevent recurrent thromboembolism in patients with a lupus antico...

heparin was isolated from whole clam tissue marcia opima . purification of multimilligram quantities of heparin from this tissue sample permitted a thorough examination of its anticoagulant activity characterization, which was partially purified by fractionation by anion exchange chromatography using deae cellulose column. the isolated crude and partially purified fractionated sample showed met...

Platelet aggregation inhibitory effect and anticoagulant properties of fractions separated from the venoms of Cerastes persicus fieldi and Echis carinatus were investigated. The partial fractionation was performed on a Sephadex G-100 column. Two fractions separated from Cerastes persicus fieldi showed anti platelet aggregation activity on ADP (200 µM)-induced platelet aggregation (ca 80% inhibi...

This is a report of a case with unilateral cavernous sinus thrombosis due to ipsilateral ethmoid sinusitis. A 10 year old female was admitted in our hospital with severe headache, purulent postnasal discharge, right eye proptosis and third cranial nerve palsy in the same eye. She had history of viral upper respiratory tract infection and then acute otitis media which did not improve with rou...

platelet aggregation inhibitory effect and anticoagulant properties of fractions separated from the venoms of cerastes persicus fieldi and echis carinatus were investigated. the partial fractionation was performed on a sephadex g-100 column. two fractions separated from cerastes persicus fieldi showed anti platelet aggregation activity on adp (200 µm)-induced platelet aggregation (ca 80% inhibi...