نتایج جستجو برای: antiacetyl cholinesterase
تعداد نتایج: 4737 فیلتر نتایج به سال:
The presence of enzymes in mammalian blood which hydrolyze acetylcholine was first suspected by Dale (1)) and later demonstrated by Plattner (2) and by Engelhart and Loewi (3). A serum cholinesterase isolated by Stedman et al. (4) from horse blood was first thought to be the same as the cholinesterase in the central nervous system.’ Distinct differences between the cholinesterase of erythrocyte...
BACKGROUND The prescribing cascade model involves the misinterpretation of an adverse reaction to 1 drug and the subsequent, potentially inappropriate prescription of a second drug. We present a new example of the prescribing cascade involving cholinesterase inhibitors and anticholinergic drugs used to manage urinary incontinence. METHODS A population-based retrospective cohort study was carr...
The cholinesterase activity of skeletal muscle and its subcellular components, including motor endplates, was compared chemically in human, mouse and rat. The total cholinesterase activity of muscle per unit protein was in the descending order of human, mouse and rat. Cholinesterase was present in all subcellular components fractionated by differential centrifugation, and was greatest in the mi...
Background: Organophosphates use in agriculture and concern about their effects on human is increasing. This study was conducted to investigate the activity of blood cholinesterase in sprayers. Methods: In a descriptive and analytical cross-sectional study, 60 (30 sprayers and 30 control individuals) with age range of 29-62 years, mean age of 44.33±8.55 years were studied and the results were ...
The in vitro effect of procainamide on plasma cholinesterase (PCHE) activity in the plasma of ten normal ASA physical status I patients was studied using a kinetic method. The mean plasma cholinesterase activity without procainamide (control) was 0.90 +/- 0.09 units.ml-1. The dibucaine numbers of all the samples were in the normal range of 78 to 86, indicating normal genotypes. The mean plasma ...
Cholinesterase activity was estimated in the serum of a Trinidadian female of Asian Indian descent. Her serum cholinesterase was pathologically low (0.17 U/ml) compared to the average reported for the population (10.59 ± 2.77 U/ml), and her dibucaine number could not be estimated. In a pedigree study her sister displayed similar enzyme activity and cholinesterase was 0.09 U/ml. Cholinesterase c...
The genus Sarcococca is widely distributed in South-East Asia and it comprises 14 species. The genus is traditionally used for gastrointestinal ulcers, infections, pain and in rheumatic fevers. Recently, our group has derived a comprehensive SAR relationship picture for a new series of natural cholinesterase inhibitors isolated from Sarcococca saligna (syn. S. pruniformis, Buxaceae). The fracti...
Previous investigators (Frawley, Hagan & Fitzhugh, 1952; Davison, 1955; Kewitz & Nachmansohn, 1957) have observed that the rate of recovery in vivo of inhibited brain true cholinesterase depended on which inhibitor was used. With diiwopropyl phosphorofluoridate (Frawley et al. 1952; Davison, 1955; Kewitz & Nachmansobn, 1957) recovery was slow, whereas with tetraethyl pyrophosphate (Davison, 195...
The genus Sarcococca is widely distributed in South-East Asia and it comprises 14 species. The genus is traditionally used for gastrointestinal ulcers, infections, pain and in rheumatic fevers. Recently, our group has derived a comprehensive SAR relationship picture for a new series of natural cholinesterase inhibitors isolated from Sarcococca saligna (syn. S. pruniformis, Buxaceae). The fracti...
BACKGROUND Farmworkers can be exposed to a wide variety of pesticides. Assessing cholinesterase activity over time can be used to monitor exposure to organophosphorus and carbamate pesticides. OBJECTIVES The goal of this study was to document patterns and variation in cholinesterase levels across the agricultural season (May-August) among field-workers, and to explore the association of choli...
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