The objective of this study was to assess the structure, anti-tyrosinase activity, and mechanism of proanthocyanidins extracted from Rhododendron pulchrum leaves. Results obtained from mass spectra of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) and high performance liquid chromatography electrospray ionization mass spectrometry (HPLC-ESI-MS) revea...

Tyrosinase is a key enzyme in melanin production. Therefore, tyrosinase inhibitors are used in cosmetic and medicinal industries to prevent or treat overproduction of melanin such as melasma, solar lentigo and post inflammatory melanoderma. Due to safety of natural whitening agents, in the present study, in-vitro anti-tyrosinase and in-vivo anti-melanogenesis activities of some selected red mac...

Tyrosinase is a key enzyme in melanin production. Therefore, tyrosinase inhibitors are used in cosmetic and medicinal industries to prevent or treat overproduction of melanin such as melasma, solar lentigo and post inflammatory melanoderma. Due to safety of natural whitening agents, in the present study, in-vitro anti-tyrosinase and in-vivo anti-melanogenesis activities of some selected red mac...

We evaluated the antioxidant activity and anti-melanogenic effects of Oenothera laciniata methanol extract (OLME) in vitro by using melan-a cells. The total polyphenol and flavonoid content of OLME was 66.3 and 19.0 mg/g, respectively. The electron-donating ability, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging activity, and superoxide dismutase (SOD)-like act...

Background and objectives: Tyrosinase is a copper containing oxidase which is crucial for controlling the production of melanin in creatures such as bacteria, fungi, plants and mammals. It is involved in the first two steps of melanin biosynthesis and leads to pigmentation and different types of cancer such as melanoma. Also, it is responsible for browning of fruits and vegetab...

Here, we investigated the anti-oxidant and anti-aging effects of essential oils (EOs) from the leaves of Alpinia zerumbet (tairin and shima) in vitro and anti-melanogenic effects in B16F10 melanoma cells. The anti-oxidant activities were performed with 2,2-diphenyl-1-picrylhydrazyl (DPPH); 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS); nitric oxide; singlet oxyge...

The aims of this study were to induce calli from the seeds three rice varieties (Hommali 105, Munpu, and Niawdum) investigate their anti-aging potential. First, cultured on a Murashige Skoog medium (MS medium) supplemented with 2 mg/L 2,4-Dichlorophenoxyacetic acid (2,4-D), 1 1-Naphthalene acetic (NAA), 6-Benzylaminopurine (BAP). After weeks, extracted ethanol. Then, phenolic contents determine...

The psychosocial burden akin to cutaneous conditions such as cancer and hyperpigmentation disorders, make their management very sensitive. Current therapeutic interventions, are associated with side-effects, cost, invasiveness bioavailability issues. Herein, 26 new pyrazole pyrazolone compounds were synthesized via microwave-assisted reactions pharmacokinetic parameters ADMET predicted by in-si...

In this study, total phenols (TP) and proanthocyanidins (PAs) in the leaves branches of Cinnamomum camphora were investigated, isolated PAs determined using reversed-phase high performance liquid chromatography electrospray ionization mass spectrometry (HPLC-ESI-MS). The anti-tyrosinase antioxidant activities also evaluated. Furthermore, scanning study dihydroxyphenylalanine (L-DOPA) oxidation ...

Abstract Seaweeds have been identified as a valuable source of natural ingredients and their use in cosmetics is being studied increasingly. This work sought to understand the possible uses three species brown algae present along Portuguese coast: Bifurcaria bifurcata , Saccorhiza polyschides Fucus spiralis . Considering idea more sustainable resources, two extracts (water (W) ethanol (E)) frac...