This study was performed to establish anti-diabetic and anti-oxidant properties, carry out phytochemical analysis of selected local plants which are traditionally used as medicinal plants. Local involved in this were Lawsonia inermis, Punica granatum, Dryobalanops aromatica, Ziziphus mauritiana, Ocimum basilicum. Solvent extraction using maceration method with solvents increasing polarity. Alph...

The control of intestinal α-amylase and α-glucosidase is an effective therapeutic strategy for prevention post-prandial hyperglycemia associated with diabetes mellitus. objective this study was to evaluate the anti-diabetes activities Korean edible seaweed against α-glucosidase, two carbolytic enzymes involved in serum glucose regulation. Of 41 species initially screened, Cladophora wrightiana ...

Long-term type 2 diabetes can lead to numerous biological complications, such as hypertension and cardio-vascular disease. Key enzymes involved in the enzymatic breakdown of complex carbohydrates,pancreatic alpha-amylase and intestinal alpha-glucosidase, have been targeted as potential avenues for modulation of type 2 diabetes-associated post-prandial hyperglycemia through mild inhibition of th...

BACKGROUND The phytochemistry and bioactivity of wetland macrophytes are underexplored. Plants are known as the natural sources of phytochemical beneficial to health. OBJECTIVE The objective of this study is to analyze the phytochemical profiles and bioactivities of 10 extracts prepared from different plant parts of wetland macrophytes Hanguana malayana, Ludwigia adscendens and Monochoria has...

Sargassum serratifolium C. Agardh (Phaeophyceae, Fucales) is a marine brown alga that belongs to the family Sargassaceae. It is widely distributed throughout coastal areas of Korea and Japan. S. serratifolium has been found to contain high concentrations of plastoquinones, which have strong anti-cancer, anti-inflammatory, antioxidant, and neuroprotective activity. This study aims to investigate...

In addition to their clinical importance in the treatment of type II diabetes, a-glucosidase inhibitors have attracted considerable attention from the synthetic community because of their profound effect on an array of cellular processes, including N-linked glycoprotein processing and maturation, oligosaccharide metabolism, and cell–cell and cell–virus recognition. Over the past decade, a numbe...

Background: In Nigeria, the leaves of Manihot esculenta (Crantz) are eaten as vegetables. The leaves are rich in phytochemicals, valuable and natural sources of antioxidants, and are highly useful for human health and disease prevention. This study was aimed to evaluate the in vitro inhibitory effects of two extracts derived from the plant leaves on α-glucosidase and α-amylase. The total flavon...

Abstract Curcuma longa is an important dietary plant which possess several pharmacological activities, including antioxidant, antimicrobial, anti-inflamatory, anticancer and anti clotting etc. The aim of the present study was to determine phenolic profile in vitro antioxidant antidiabetic activities. In HPLC chromatogram rhizome extract 15 compounds were identified namely Digalloyl-hexoside, Ca...

The nano sized copper oxide material (CuONPs) were prepared by the greener way and an approach functionalized polymer using Sarcostemma acidum stem extracts. in-vitro anti-diabetic activity was studied through α-glucosidase α-amylase inhibitory methods demonstrated in stem, biological synthesized CuONPs polymerized CuONPs. percentage inhibition at 100 μg/ml, 200 300 400 μg/ml 500μg/ml concentra...

Homalium zeylanicum (Gardner) Benth. (Flacourtiaceae) is a medicinal plant useful in controlling rheumatism, inflammation and diabetes. The objective of this work evaluates in vitro antioxidant, antidiabetic, and antiinflammatory properties of hydroalcohol extract of bark of H. zeylanicum (HAHZ). It also describes isolation and structure determination of lucidenic acid A, which is the first rep...