OBJECTIVE The present investigation aims to evaluate the prevalence of IgM and IgG anti-T. gondii antibodies and the associated risk factors among healthy blood donors in Mashhad city, Razavi Khorasan province, Iran. METHODS We screened a total of 500 serum samples by census method from apparently healthy blood donors of the Mashhad Blood Transfusion Organization (MBTO) for IgG and IgM anti-T...

OBJECTIVE Nyctereutes procyonoides immunoglobulin G (IgG) gene is partially cloned. MATERIAL AND METHODS In order to obtain a certain length (966bp) of Nyctereutes procyonoides immunoglobulin G (IgG), two pairs of primers are designed according to the conserved nucleotide sequence of canine (GenBank:AF354265, AF354265, AF354266, AF354267) and mink (GenBank: L07789). Using Bioinformatics techn...

Local and systemic immune responses were studied in six dogs experimentally infected with the dog/sheep tapeworm Echinococcus granulosus. All dogs developed similar IgG antibody response to parasite antigens. In contrast, IgE and IgA responses differed widely. No relationship between IgA responses and parasite burden at the end of the infection were observed. Further, clear differences in the a...

Background: Neuromyelitis optica spectrum disorder (NMOSD) is a clinically defined, inflammatory central nervous system (CNS) disease of unknown cause, associated with humoral autoimmune findings such as anti-aquaporin 4 (AQP4)-IgG. Recent clinical trials showed benefit anti-B cell and anti-complement-antibodies in NMOSD, suggesting relevance anti-AQP4-IgG pathogenesis. Objective: AQP4-IgG NMOS...

Sốt xuất huyết Dengue là một bệnh truyền nhiễm cấp tính do virus gây ra, lây qua muỗi Aedes. Nghiên cứu này đánh giá số đặc điểm học, chức năng gan, kháng thể ở 253 nhân (BN) sốt Dengue. Kết quả nghiên cho thấy chỉ anti-DENV-IgM, anti-DENV-IgG thay đổi rõ rệt giữa nhóm (DF) và có dấu hiệu cảnh báo (DWS) (p<0,05). Có mối liên quan tăng hoạt độ ALT AST, giảm lượng tiểu cầu DF hoặc anti-DENV-Ig...

objective anti-rh d igg is used for the prevention of anti-d antibody production in rh- individuals who have been exposed to rh+ red blood cells. the stability of igg preparations as a solution is low, with a shelf life of a year or more. formulation of anti-rh d igg as a lyophilized preparation would decrease its degradation rate and increases its shelf life. the objective of this study was to...

background: the prevalence of toxoplasma gondii infection in the blood donors has been poorly studied. the aim of this study was to assess the prevalence of acute and chronic toxoplasmosis in blood products. methods: a total of 250 blood products (112 fresh frozen plasma and 138 packed cells) in the blood transfusion institute, shiraz, iran were tested for spe-cific t. gondii antibodies (igg an...

in this study, 16 eligible dogs were randomly divided in to 4 groups. group 1, 2, 3 and 4 received autoclaved leishmania infantum with bcg (ali+bcg), autoclaved leishmania major + bcg (alm + bcg), bcg alone and normal saline, respectively. dogs received the vaccines intradermally 3 times at 30 days intervals. all dogs were followed up 2 months intervals by leishmanin skin test and anti -leishma...