Antimalarial treatment is often associated with the resistance developed by Plasmodium which generate ineffective drug treatment. Based on this, search for therapeutic alternatives necessary and urgent. This review intends to assess antimalarial potential of quinones isolated from plants. The scientific articles was carried out CAPES Journal Portal (PPC), Virtual Health Library (VHL), PUBMED, N...

Aloe vera (Aloe barbadensis Miller) is widely spread around the world and it used in food cosmetic industry traditional medicine due to its high content bioactive compounds. Thus, this article investigated phenolic compounds of Romanian gel antioxidant capacity. The was extracted using 4 different solvents: methanol, ethanol, water, acetone. Total phenolics were measured by Folin-Ciocalteu meth...

Several species of Senna are well known for their therapeutic properties, being used in folk medicine to treat throat inflammation and constipation. In this regard, the anti-inflammatory, laxative and intestinal motility effects of different extracts of Senna macranthera (Colladon) H. Irwin and Barneby leaves were determined. The hexane extract significantly reduced carrageenan-induced paw oede...

Danning Tablets are a traditional Chinese formula showing broad clinical applications in hepatobiliary diseases and containing a diversity of bioactive chemicals. However, the chemical profiling of the formula, which serves as the material foundation of its efficacy, is really a big challenge as Danning Tablets consist of seven herbs from different origins. An ultra-performance liquid chromatog...

Eleusine indica, a perennial herb that belongs to the Poaceae family, is locally known as “rumput sambau”. The species can be found in tropical regions and it only of Malaysia. In India, some parts plant such roots seeds are used food eaten raw or cooked. young seedling also side dish with rice, while sometimes famine food. Although this grass not considered Malaysia, local people utilise treat...

The syntheses, the biological evaluation, and the structure-activity relationships of a novel series of 1,8-dihydroxy-9(10H)-anthracenones bearing acyl-, alkyl-, or alkylidene-linked aromatic substituents in the 10-position are described. The phenylacyl and phenylalkylidene analogs were far more potent inhibitors of 5-lipoxygenase (5-LO) from bovine polymorphonuclear leukocytes (IC50 values in ...

BACKGROUND The incidents of drug resistant microorganisms and the need of treatments for newly emerging pathogens are of great concern to the global community. Our ability to treat infectious diseases is dependent on the development of new pharmaceuticals, and one potential source being medicinal plants with traditional claims. The leaves of Aloe trigonantha L.C. Leach, an endemic Ethiopian pla...

Treatment of 10-bromoanthralin (1) with several thiophenols (2) gave the corresponding 10-arylthioanthralins (3) in high yields. Oxidation of thioanthralins (3a-c) and (3k-m) using an excess of m-chloroperbenzoic acid gave the corresponding sulfones (4a-c) and (4k-m) in good yields. Oxidation of thioanthralins (3d-f) gave a mixture of the corresponding sulfones (4d-f) and anthralin-10,10'-d...

BACKGROUND AND PURPOSE OF THE STUDY Fabaceae is the third largest family of flowering plants. Lack of essential oils in the plants of this family can be an advantage in search for safe and effective medicines. In this study the anticonvulsant effect of the leaves of Albizzia julibrissin, Acacia juliflora, Acacia nubica and aerial parts of Astragalus obtusifolius was evaluated in pentylenetetraz...

diseases in the world. It constitutes a public health problem in more than 90 countries, inhabited by about 40% of the world’s population. The World Health Organisation estimates that there are 300—500 million malaria cases annually, causing 2—3 million deaths, mostly in children under five years old. Africa accounts for over 90% of malaria mortality. Malaria also has significant economic impac...