Objectives: Anorexia is one among the most prevalent conditions triggering malnutrition, drastic weight loss and serious health issues in people especially older adults. Habb-e-Hilteet commonly prescribed Unani pharmacopoeial formulation for anorexia. However, no scientific data available as to its safety efficacy. The current study assessed appetite-inducing effect of Ḍu‘f al-Ishtihā (anorexia...

BACKGROUND Patients with anorexia nervosa exhibit higher levels of behaviours typically associated with autism-spectrum disorder (ASD), but the neural basis is unclear. We sought to determine whether elevated autistic traits in women with anorexia nervosa may be reflected in cortical morphology. METHODS We used voxel-based morphometry (VBM) to examine regional grey matter volumes in high-reso...

Anorexia nervosa is a perplexing illness marked by low body weight and persistent fear of weight gain. Anorexia nervosa has the highest mortality rate of any psychiatric disease. Historically, anorexia nervosa was viewed as a disorder primarily influenced by sociocultural factors; however, over the past decade, this perception has been challenged. Family studies have consistently demonstrated t...

BACKGROUND The neurobiology of anorexia nervosa is poorly understood. Neuronal networks contributing to action selection, self-regulation and interoception could contribute to pathologic eating and body perception in people with anorexia nervosa. We tested the hypothesis that the salience network (SN) and default mode network (DMN) would show decreased intrinsic activity in women with anorexia ...

During infection it is very common to lose one’s appetite (anorexia) and reduce nutrient intake. Anorexia is one of a group of symptoms collectively termed sickness behaviors, which in turn are a part of the acute-phase response (APR). The APR and its components, including anorexia, fever and iron sequestration, are induced by pro-inflammatory cytokines, e.g. interleukin-6, interleukin-1 and tu...

OBJECTIVE The purpose of this study was to examine the role of perfectionism as a phenotypic trait in anorexia nervosa and its relevance across clinical subtypes of this illness. METHOD The Multidimensional Perfectionism Scale and the perfectionism subscale of the Eating Disorder Inventory were administered to 322 women with a history of anorexia nervosa who were participating in an internati...

Although patients with anorexia nervosa (anorexia) are known to show tubulointerstitial nephritis (TIN), the pathophysiology of its progression is not fully understood. We herein report a 31-year-old woman with anorexia who showed acute exacerbation of chronic kidney disease. Renal biopsy showed non-uniform chronic TIN; some areas were obsolete lesions and other areas were active lesions. In ad...

The anorexia of aging was first recognized as a physiological syndrome 30 years ago. Its major causes are an alteration in fundal compliance with an increase in antral stretch and enhanced cholecystokinin activity leading to increased satiation.This anorexia leads to weight loss in aging persons and is one of the component causes of the aging related sarcopenia. This physiological anorexia also...

Anorexia nervosa is one of the important problems of the adolescent gynecology. We report on a patient aged 17 years with anorexia nervosa associated with gynecological problems. This paper presents sociocultural and medical aspects of anorexia nervosa.