With the advent of the genomic revolution and the sequencing of the human genome complete, the majority of pharmaceuticals under development are proteins. Consequently, new techniques to more effectively administer these new protein therapeutics need to be developed. One method that is gaining popularity in the research community involves the use of responsive hydrogel actuators for flow contro...

OBJECTIVE To assess the prevalence, mechanisms, and significance of paraprosthetic regurgitation detected incidentally by transoesophageal echocardiography (TOE) in patients after heart valve replacement. DESIGN Prospective observational study. SETTING Tertiary referral centre. PATIENTS 360 consecutive patients (mean (SD) age 65.8(9.5) years, 193 women) undergoing elective first ever valv...

Globe valves are one of the oldest types of valve used for throttling applications for all sizes due to better controllability and wider range. One of the major limitations associated with the use globe valves in liquid application is cavitation and it takes place both in part open and in fully open conditions due to varied reasons. There are different designs of globe valves available but for ...

BACKGROUND Bicuspid aortic valves (BAVs) are associated with premature valve stenosis, regurgitation, and ascending aortic aneurysms. We compared aortic size in BAV patients with aortic size in control patients with matched valvular lesions (aortic regurgitation, aortic stenosis, or mixed lesions) to determine whether intrinsic aortic abnormalities in BAVs account for aortic dilatation beyond t...

Chronic ossified epidural hematoma is an uncommon complication of ventricular shunt operation, and bilateral chronic ossified epidural hematoma was rare to reported in the literature. We report a 35-year-old man with triventricular hydrocephalus was treated with a ventriculoperitoneal shunt but presenting with chronic epidural hematoma at 3 days reexamination after operation. At that time, the ...

Lower cost, higher control performance and significantly less energy consumption are the goals for the design of any industrial systems including electro-hydraulics. The paper presents an integrated mechatronic design approach – seamless integration of advanced control techniques with novel hardware reconfiguration/re-design – as one of the tools to achieve these lofty goals simultaneously. The...

T here has been a trend toward more frequent use of biopros-thetic valves, especially in the young generations, over the last decade. 1 Freedom from warfa-rin use and restrictions on diet and activities make bioprosthetic valves more attractive and popular, and multiple reports have shown that choosing a bioprosthetic valve does not decrease survival despite the increased rate of reoperation. T...

Novel pollutant control equipment, which were called integrated pollutant control equipment, consisted of bag filters and activated carbon (AC) absorbers. The AC absorbers were put forward to absorb the additional pollutants between the old and new emission standards to satisfy Chinese emission standards. The absorbers could be fixed (mobile) bed, annular column, or fluidized bed. The numerical...