The nematode cuticle is a protective collagenous extracellular matrix (ECM) that is modified, cross-linked and processed by a number of key enzymes. This Ecdyzoanspecific structure is synthesized repeatedly and allows growth and development in a linked degradative and biosynthetic process known as molting. A targeted RNAi screen using a cuticle collagen marker has been employed to identify comp...

background: to use different methods for serodiagnosis of ruminants' haemonchosis is important because detection of egg in the faeces is not so reliable. methods: peptide bands of 5 different crude antigens of intestine, uterus, cuticle, whole male and whole female of hae­monchus contortus were determined using sds-page and western blotting. five lambs were infected with 10,000 third stage larv...

Bone morphogenetic protein (BMP) pathway signaling plays a critical role in extracellular growth and homeostasis, including basement membrane remodeling and long bone growth. In the small free-living nematode C. elegans, BMP signaling regulates body size development and drug response through an unknown physiological mechanism. Our lab and others have shown animals lacking BMP signaling (bmp(-))...

Although thiotrophic symbioses have been intensively studied for the last three decades, nothing is known about the molecular mechanisms of symbiont acquisition. We used the symbiosis between the marine nematode Laxus oneistus and sulfur-oxidizing bacteria to study this process. In this association a monolayer of symbionts covers the whole cuticle of the nematode, except its anterior-most regio...

A key aspect of animal development is the appropriate polarisation of different cell types in the right place at the right time. Such polarisation is often precisely coordinated relative to the axes of a tissue or organ, but the mechanisms underlying this coordination are still poorly understood. Nevertheless, genetic analysis of animal development has revealed some of the pathways involved. Fo...

UNLABELLED Circularly polarized light, rare in the animal kingdom, has thus far been documented in only a handful of animals. Using a rotating circular polarization (CP) analyzer we detected CP in linearly polarized light transmitted through epipelagic free living Sapphirina metallina copepods. Both left and right handedness of CP was detected, generated from specific organs of the animal's bod...

The cuticle is a unique invisible oviduct secretion that protects avian eggs from bacterial penetration through gas exchange pores. Despite its importance, experimental evidence is lacking for where, when, and what is responsible for its deposition. By using knowledge about the ovulatory cycle and oviposition, we have manipulated cuticle deposition to obtain evidence on these key points. Cuticl...

Cell adhesion molecules and their extracellular ligands control morphogenetic events such as directed cell migration. The migration of neuroblasts neural crest cells establishes the structure central peripheral nervous systems. In C. elegans, bilateral Q descendants undergo long-range migrations with left/right asymmetry. QR its on right migrate anteriorly, QL left posteriorly, despite identica...

0003-3472 2010 The Association for the Study of A doi:10.1016/j.anbehav.2010.11.020 Social insects use cuticular lipids for nestmate recognition. These lipids are chiefly hydrocarbons that can be endogenously produced or acquired from the environment. Although these compounds are already described as coming from different sources for different groups of social insects, nothing is known about th...