نتایج جستجو برای: angiogenic aktmtorp70s6k mechanism
تعداد نتایج: 580410 فیلتر نتایج به سال:
In the present study we evaluated the anti-angiogenic activities of β-escin (the major active compound of Aesculus hippocastanum L. seeds). Human umbilical-vein endothelial cells (HUVECs) were used as an in vitro model for studying the molecular mechanism underlying the anti-angiogenic effect of β-escin. We investigated the in vitro effects on proliferation, migration, and tube formation of HUV...
neovascularization of the normally avascular cornea was associated with a notable increase in the expression of the major pro-angiogenic factors, inflammatory cytokines and proteases. the data supporting a causal role for vascular endothelial growth factor (vegf), inflammatory cytokines and matrix metalloproteinase (mmps) are extensive. anti-angiogenic/anti-inflammatory therapy is considered as...
[This article][1] ([1][2]) is being retracted at the request of authors. The images used in second and third panels CXCR4 siRNA Fig. 1B were duplicated from first PC3-control cells a previously published article that has since been ([2][
BACKGROUND MicroRNAs are key regulators of angiogenic processes. Administration of angiogenic early outgrowth cells (EOCs) or CD34(+) cells has been suggested to improve cardiac function after ischemic injury, in particular by promoting neovascularization. The present study therefore examines regulation of angiomiRs, microRNAs involved in angiogenesis, in angiogenic EOCs and circulating CD34(+)...
Angiogenesis, that is the construction of new vessels from pre-existing vessels, is a crucial event in not only physiological but also pathological conditions; for example, wound healing and the female reproductive cycle are related to it in a physiological condition. On the other hand, diabetic retinopathy and chronic inflammation are closely involved in pathological angiogenesis. In particula...
BACKGROUND Anti-angiogenic therapy in certain cancers has been associated with improved control of tumor growth and metastasis. Development of anti-angiogenic agents has, however, been saddled with higher attrition rate due to suboptimal efficacy, narrow therapeutic windows, or development of organ-specific toxicities. The aim of this study was to evaluate the translational ability of the zebra...
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