Recently, 6-(2-naphthyl)-2, 3-dihydro-as-triazine-3-thione (NDTT) was synthesized in laboratory and used successfully for the spectrophotometric determination of nanogram levels of Cu(2+) in aqueous solution. This reagent forms a specific red complex with Cu(2+) ions after the extraction by chloroform at alkaline pH. The absorption of the complex in the UV region (313 nm) is about 8 times as st...

Aviel D. Rubin (ACCURATE Director), Johns Hopkins University Dan S. Wallach (ACCURATE Associate Director), Rice University Dan Boneh, Stanford University Michael D. Byrne, Rice University Drew Dean, SRI International David L. Dill, Stanford University Douglas W. Jones, University of Iowa Peter G. Neumann, SRI International Deirdre Mulligan, University of California, Berkeley David A. Wagner, Un...

We characterize the "sequence landscapes" in several simple, heteropolymer models of proteins by examining their mutation properties. Using an efficient flat-histogram Monte Carlo search method, our approach involves determining the distribution in energy of all sequences of a given length when threaded through a common backbone. These calculations are performed for a number of Protein Data Ban...