نتایج جستجو برای: and ter stepanos
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In response to the proposal that cognitive phenomena might be best understood in terms of cognitive theories (Endress, 2013), Frank (2013) outlined an important research program, suggesting that Bayesian models should be used as rigorous, mathematically attractive implementations of psychological theories. This research program is important and promising. However, I show that it is not followed...
Although the UK and US were staunch allies before and during the Iraq War, differing sociopolitical milieus existed within the countries regarding support for the war. This cross-national content analysis compared stories on antiwar protest by leading newspapers in each country to determine if the differing sociopolitical environments were reflected in each nation’s press coverage. Results indi...
Telomerase RNA (TER) is an essential component of the telomerase ribonucleoprotein complex. The mechanism for TER 3'-end processing is highly divergent among different organisms. Here we report a unique spliceosome-mediated TER 3'-end cleavage mechanism in Neurospora crassa that is distinct from that found specifically in the fission yeast Schizosaccharomyces pombe. While the S. pombe TER intro...
یکی از دلایل استفاده از پروتئین m2e برای ساخت واکسن آنفلوانزا a توانایی منحصر به فرد آنهاست. از این رو برای افزایش مقاومت و ایمنی یک راه موثر مصون باقی ماندن پروتئین m2e است. به نظر می رسد که ما می توانیم با اتصال این m2e-peptide به یک ناقل مناسب مانند hsp70(c-ter) مایکوباکتریوم توبرکلوزیس آن را مقاوم کنیم. بنا بر گزارشات قبل ،این تحقیق در نظر دارد از ترکیب پروتئین m2e از ویروس آنفلوانزا a با ...
DNA transactions driven by long-range protein-mediated inter- and intrachromosomal interactions have been reported to influence gene expression. Here, we report that site-specific replication termination in Schizosaccharomyces pombe is modulated by protein-mediated interactions between pairs of Ter sites located either on the same or on different chromosomes. The dimeric Reb1 protein catalyzes ...
Enzyme-linked and electrochemiluminescence immunoassays were developed for quantification of amino (N-) terminal fragments of the skeletal muscle protein titin (N-ter titin) and qualified for use in detection of urinary N-ter titin excretion. Urine from normal subjects contained a small but measurable level of N-ter titin (1.0 ± 0.4 ng/ml). A 365-fold increase (365.4 ± 65.0, P = 0.0001) in urin...
Nuno C. Santos,* Evgeny Ter-Ovanesyan, Joseph A. Zasadzinski, and Miguel A. R. B. Castanho* Centro de Quı́mica-Fı́sica Molecular, Complexo I, Instituto Superior Técnico, Lisboa, Portugal; Departamento de Quı́mica e Bioquı́mica, Faculdade de Ciências da Universidade de Lisboa, Lisboa, Portugal; and Department of Chemical and Nuclear Engineering, University of California, Santa Barbara, California 93...
During the budding of coat protein complex II (COPII) vesicles from transitional endoplasmic reticulum (tER) sites, Sec16 has been proposed to play two distinct roles: negatively regulating COPII turnover and organizing COPII assembly at tER sites. We tested these ideas using the yeast Pichia pastoris. Redistribution of Sec16 to the cytosol accelerates tER dynamics, supporting a negative regula...
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