Invasive aspergillosis (IA), generally considered an opportunistic infection in immunocompromised hosts, is associated with high morbidity and mortality. IA commonly occurs in the respiratory tract with isolated reports of aspergillosis infection in the nasal sinuses, central nervous system, skin, liver, and urinary tract. Extra-pulmonary aspergillosis is usually observed in disseminated diseas...

Sixty five patients with pulmonary eosinophilia attending one respiratory unit were reviewed. All had fleeting radiographic abnormalities and peripheral blood eosinophil counts greater than 500 x 10(6)/l. Eighteen had a single episode and 47 recurrent episodes during a median follow up period of 14 years. Thirty three patients had allergic bronchopulmonary aspergillosis on the basis of a positi...

I Aspergillosis (IA) is a common opportunistic infection in immunocompromised individuals. The IA is an important cause of morbidity and mortality in patients with hematological malignancies and it is particularly common during neutropenic episodes following anticancer chemotherapy.1 While pulmonary aspergillosis involvement is common, gastrointestinal (GI) aspergillosis infection with clinical...

gastrointestinal aspergillosis most often occurs in the setting of disseminated infection from a primary pulmonary site and primary gastrointestinal aspergillosis is an unusual presentation. we report a 7 year old female child with aplastic anemia, who was under treatment but experienced periods of neutropenia. she had no evidence of respiratory aspergillosis before the onset of abdominal sympt...

We describe the case of a 9-year-old boy with idiopathic bone marrow aplasia and severe neutropenia, who developed skin ulcers under cardiac monitoring electrodes. The diagnosis of primary cutaneous aspergillosis was made after the second biopsy and culture. Imaging investigation did not reveal internal fungal infection. The child was treated, but did not improve and died 3 months after admissi...

We read with interest the review by Schulman et al 1 in a recent issue of CHEST (January 2015) wherein the authors suggest the use of a skin test for screening sensitization to various allergens in preference to specifi c IgE antibody testing in patients with asthma. We agree with the authors that all patients with asthma should be screened for allergic sensitization against a particular allerg...