INTRODUCTION Balanced analgesia, using both opioid and nonopioids agents, has become the standard care for postoperative pain management. Ketamine, a compound with analgesic and antihyperalgesic properties, has been shown to decrease postoperative pain and opioid requirements in adults. The goal of the present meta-analysis was to investigate postoperative analgesic properties of ketamine in pe...

Metoclopramide traditionally has been used as a prokinetic and antiemetic, but recently it also has been investigated as an agent to enhance analgesic efficacy. No definitive studies have been undertaken to determine whether metoclopramide can decrease postoperative analgesic requirements. The present study examined the effects of the administration of metoclopramide on the postoperative opioid...

The alpha2-agonist dexmedetomidine (Dex), a sedative and analgesic, reduces heart rate (HR) and blood pressure, and has been used in the practice of anesthesia. In this study, we aimed to evaluate the effects of Dex on hemodynamic variables, anesthetic sparing effects, and recovery profiles in patients who underwent surgery in prone position. The prone position itself can cause a decrease in th...

BACKGROUND AND PURPOSE The local infiltration analgesia (LIA) technique has been widely used to reduce opioid requirements and to improve postoperative mobilization following total hip arthroplasty (THA). However, the evidence for the efficacy of LIA in THA is not yet clear. We determined whether single-shot LIA in addition to a multimodal analgesic regimen would reduce acute postoperative pain...

Introduction: Since there is no data concerning local analgesic efficacy of ropivacaine for lower third molar surgery, the aim of this doubleblind study was to compare local anaesthetic parameters and postoperative analgesic requirements after the use of ropivacaine and bupivacaine for the inferior alveolar nerve block. Materials and Method: 20 healthy patients were equally randomised into the ...

Background: Peritonsillar infiltrations of local anesthetics and/or locally active analgesic drugs have been used in several studies for relief of post-tonsillectomy pain with variable results in quality and duration of analgesia. Aim: This study was designed to compare the effects of peritonsillar infiltration of lidocaine versus tramadol or placebo on postoperative pain after tonsillectomy. M...

BACKGROUND Reports conflict on optimal postoperative analgesic treatment in children with intellectual disability. We retrospectively compared postoperative analgesics consumption between neonates with and without Down's syndrome in relation to anaesthesia requirements and pain scores. METHODS We analysed hypnotic and analgesic drug administration, pain scores [COMFORT-Behaviour (COMFORT-B) s...

BACKGROUND We evaluated the effects of ropivacaine for pain relief after robotic thyroid surgery. METHODS One hundred eight patients scheduled for robotic thyroid surgery were randomized into ropivacaine (n = 54) or control (n = 54) groups. After surgery, 40 mL of 0.25% ropivacaine or 0.9% saline (control) was instilled into the skin flap. Postoperative pain intensity (visual analog scale [VA...

BACKGROUND Minimally invasive posterior cervical foraminotomy for radicular symptoms has become more prevalent. The reported experience with microscopic tubular assisted posterior cervical laminoforaminotomy (MTPF) for the treatment of radicular pain is lacking. Tubular assisted techniques have been considered to offer significant benefit, over open procedures, in terms of minimizing tissue dam...