The proteoglycans and glycosaminoglycans synthesized by embryonic mouse salivary glands during normal morphogenesis and in the presence of beta-xyloside, an inhibitor of branching morphogenesis, have been partially characterized. Control and rho-nitrophenyl-beta-D-xyloside-treated salivary rudiments synthesize proteoglycans that are qualitatively similar, based on mobility on Sepharose CL-4B un...

Terpene composition of needle and cortical oleoresin from lateral shoots were analyzed by GC/MS for four Silver fir (Abies alba Mill.) populations scattered in natural species range in Albania. More than sixty compounds were detected in the needle oleoresin, which was characterized by a high content of alpha-pinene, camphene, beta-pinene, limonene and bornyl acetate. Three monoterpenes, alpha-p...

Cultured human embryonic lung fibroblasts were used as a model to study the effects of transforming growth factor-beta (TGF beta) on the plasminogen activator (PA) activity released by nontumorigenic cells into the culture medium. The cells were exposed to TGF beta under serum-free conditions, and the changes in PA activity and protein metabolism were analyzed by caseinolysis-in-agar assays, zy...

Beta Thromboglobulin plasma levels were measured in three groups of hospital patients; a control group (n = 13) of non-drinkers, and test groups of patients who from their medical history regularly consumed either moderate amounts (80-200G/24 hours n = 31) or large amounts (200G/24 hours n = 10) of alcohol. Significant differences were detected between the control group, and both groups of drin...

We study the probability that one beta-distributed random variable exceeds maximum of two others, allowing all three to have general parameters. This amounts studying Euler transforms products incomplete beta functions. provide a closed form for problem in terms Kampé de Fériet functions and variety simpler forms special cases. The results are applied derive moments independent variables find i...

The role of peroxyl radicals and cytochrome P-450 in the metabolic activation of the (+)-enantiomer of 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene [(+)-BP-7,8-diol] was investigated in the epidermis of CD-1 mice. In skin homogenates from untreated or acetone-pretreated animals [7-14C]-(+)-BP-7,8-diol (20 microM) was metabolized primarily to 7 alpha,8 beta-dihydroxy-9 beta,10 beta-epoxy-7,8,9,10-tet...

A cDNA clone for the Golgi enzyme 4 beta-galactosyltransferase (EC 2.4.1.38) was used to determine the steady-state mRNA content in cultured rat parotid acinar cells. Isoprenaline, a beta-adrenergic-receptor agonist, caused an increase in steady-state amounts of mRNA for 4 beta-galactosyltransferase in cultured acinar cells as well as in specific activity of the enzyme. The amount of 4 beta-gal...

Globin messenger RNA (mRNA) isolated from three patients homozygous for hemoglobin Lepore is shown to have a marked reduction of the amount of beta-like globin mRNA (Lepore-globin mRNA sequences) compared with alpha-globin mRNA by molecular hybridization. The relative amounts of alpha- and Lepore mRNA are similar to the amounts of alpha- and Lepore globin synthesized in intact cells and by isol...

Transforming growth factor beta 1 (TGF-beta 1) switches from an inhibitor of tumor cell growth to a stimulator of growth and invasion during human colon carcinoma progression. We originally observed that metastatic colon carcinoma cells in primary culture responded to TGF-beta 1 by proliferation, whereas moderate to well-differentiated primary site colon carcinomas were growth inhibited by TGF-...