The methyl–amide complex [TaCp*(NBu)Me(NMe2)] (1a) was isolated by reaction of the chloro–methyl [TaCp*(NBu)MeCl] complex with LiNMe2. Reaction of the mono-amide compounds [TaCp*(N Bu)XY] (X=NMe2, Y=Me (1a); X=NHBu, Y=Me (1b), Cl (1c)) with CO2 gives the h-carbamate derivatives [TaCp*(NBu)(h-O2CX)Y] (X=NMe2, Y=Me (2a); X=NHBu, Y=Me (2b), Cl (2c)). A similar reaction with the di-amide complex [T...

nano silica-h2so4 is an efficient and mild catalysis system for the regeneration of aldehyde from aldoximes. ketoximes are converted to amides by beckmann rearrangement in the presence of nano silica-h2so4. the reactions are carried out in solvent-free conditions under microwave irradiation (600 w) within 50-120 sec in good yields.

The synthesis of a bis(amino)amide nickel pincer complex bearing a perfluoroethyl ligand was effected by reaction of the corresponding nickel chloride complex with cesium fluoride and trimethyl(pentafluoroethyl)silane. Electrochemical experiments revealed that the oxidation of the LNi-C(2)F(5) complex occurs at the same potential as the LNi-Cl derivative, but reduction of the LNi-C(2)F(5) compl...

Complex flower-shaped superstructures (FSSs) have rarely been reported in pure organic systems with a single soft molecule without rigid skeletons. Herein, simple self-assembled complex FSSs using amphiphilic cyclosiloxane amphiphiles are obtained through drop-casting solution process. The synergetic effect of amide–amide hydrogen bonding/alkyl hydrophobic interactions can be tuned to generate ...

The uranyl amide [{Li(DME)}(2)Cl][Li(DME)][UO(2)(NC(5)H(10))(3)](2) has been synthesised and structurally characterised. Its stability is attributed to the saturation of the uranyl coordination sphere by "ate" complex formation.

Amide hydrogen exchange has been used to examine the structural dynamics and energetics of the interaction of a peptide corresponding to the calmodulin-binding domain of smooth muscle myosin light chain kinase (smMLCKp) with calcium-saturated calmodulin. Heteronuclear NMR (15)N-(1)H correlation spectroscopy was used to quantify amide proton exchange rates of the uniformly (15)N-labeled domain b...

BACKGROUND Protegin-1 (PG-1: RGGRLCYCRRRFCVCVGR-amide) assumes a rigid β-hairpin like structure that is stabilized by two disulfide bridges between Cys6-Cys15 and Cys8-Cys13. Previous studies, employing linear analogs of PG-1, with Cys to Ala mutations or modified Cys, have demonstrated that the disulfide bridges are critical for the broad spectrum and salt resistant antimicrobial activity of P...

In mass spectrometry of protonated N-phenylcinnamides, the carbonyl oxygen is the thermodynamically most favorable protonation site and the added proton is initially localized on it. Upon collisional activation, the proton transfers from the carbonyl oxygen to the dissociative protonation site at the amide nitrogen atom or the α-carbon atom, leading to the formation of important reactive interm...