objective(s): brain edema is one of the most serious causes of death within the first few days after trauma brain injury (tbi). in this study we have investigated the role of shilajit on brain edema, blood-brain barrier (bbb) permeability, intracranial pressure (icp) and neurologic outcomes following brain trauma.   materials and methods: diffuse traumatic brain trauma was induced in rats by dr...

background: in previous studies, the neuroprotective effect of 17&beta-estradiol; in diffuse traumatic brain injury has been shown. this study used ici 182,780, a non-selective estrogen receptor antagonist, to test the hypothesis that the neuroprotective effect of 17&beta-estradiol; in traumatic brain injury is mediated by the estrogen receptors. methods: the ovariectomized rats were divided in...

In this article, we present the case of a 12-year-old female child who complained of bilateral temporal and frontal headache for 2 to 3 months with nausea and vomiting. Physical examination revealed right-sided sixth cranial nerve palsy and papilledema in ophthalmoscopy. To find the cause of increased intracranial pressure, the patient underwent brain imaging and brain MRI showed no abnormality...

in this article, we present the case of a 12-year-old female child who complained of bilateral temporal and frontal headache for 2 to 3 months with nausea and vomiting. physical examination revealed right-sided sixth cranial nerve palsy and papilledema in ophthalmoscopy. to find the cause of increased intracranial pressure, the patient underwent brain imaging and brain mri showed no abnormality...

Several studies have shown that the progression of communicating hydrocephalus is associated with diminished cerebral perfusion and microangiopathy. If communicating hydrocephalus similarly alters the cerebrospinal fluid circulation and cerebral blood flow, both may be related to intracranial mechanoelastic properties as, for instance, the volume pressure compliance. Twenty-three shunted patien...

In twelve anaesthetised, ventilated dogs the effects of hypercapnia and pharmacologically induced arterial hypotension and hypertension on the interrelation between volume-pressure response (VPR) and cerebro-spinal fluid (CSF) pulse pressure were studied during continuous inflation of a supratentorial extradural balloon. Hypercapnia did not significantly affect the intracranial volume-pressure ...

  Background :There is not any data available about the effect of high bar pressure condition on intracranial pressure. In this study, the effect of diving on the optic nerve and sheath diameters as non-invasive markers of intracranial pressure has been investigated.   Methods : Twenty professional male divers from twenty one volunteers were chosen for this cross-sectional study. Only one perso...

The mathematical model presented in a previous work is used to simulate the time pattern of intracranial pressure (ICP) and of blood velocity in the middle cerebral artery ( V MCA) in response to maneuvers simultaneously affecting mean systemic arterial pressure (SAP) and end-tidal CO2pressure. In the first stage of this study, a sensitivity analysis was performed to clarify the role of some im...

The effect of methoxyflurane 0.5 per cent and 1.5 per cent on cerebrospinal fluid (c.si.) pressure has been studied in patients with normal c.s.f. pathways and in patients with intracranial space-occupying lesions. In patients with normal c.s.f. pathways, methoxyflurane 0.5 per cent produced variable responses, causing small increases in c.si. pressure in some and small decreases in others. On ...

intracranial hypertension is the largest cause of death in young patients with severe traumatic brain injury. decompressive craniectomy is part of the second level measures for the management of increased intracranial pressure refractory to medical management as moderate hypothermia and barbiturate coma. the literature lack of concepts is their indications. we present a review on the state of t...