S-Alk(en)yl-L-cysteine sulfoxides are pharmaceutically important secondary metabolites produced by plants that belong to the genus Allium. Biosynthesis of S-alk(en)yl-L-cysteine sulfoxides is initiated by S-alk(en)ylation of glutathione, which is followed by the removal of glycyl and γ-glutamyl groups and S-oxygenation. However, most of the enzymes involved in the biosynthesis of S-alk(en)yl-L-...

Thiosulfinates, a substance of Allium tuberosum L., is a known folk medicine that has been extensively used in diet to treat diseases. In the present study, we have evaluated the effect of thiosulfinates from Allium tumberosum L. on proliferation of metastasis (DU145) and primary malignant tumor (RC-58T/h/SA#4)-derived human prostate cancer cells. Thiosulfinates decrease viable cell numbers in ...

Singh VK, Singh DK. Pharmacological Effects of Garlic (Allium sativum L.). ARBS Annu Rev Biomed Sci 2008;10:6-26. Garlic (Allium sativum L.) is a bulbous herb used as a food item, spice and medicine in different parts of the world. Its medicinal use is based on traditional experience passed from generation to generation. Researchers from various disciplines are now directing their efforts towar...

The aim of this study was to evaluate plant extracts for antifungal activities against Phythopthora infestans (Mont.) de Bary, an important pathogen of potato which causes late blight disease. Acetone, ethyl acetate and water extracts of garlic (Allium sativum L.), Pawpaw (Carica papaya), Neem (Azadirachta indica), Mexican marigold (Tagetes minuta) and peri –winkle (Vinca rosea) were screened i...

Since L. Guignari's investigation (1884) various investigators have reported the studies on plants in the genus Allium of Liliaceae, as some species in this genus are cultivated and are noteworthy from the cytological point of view. According to T. Suto's papers (1936, 1936) on the phylogenetic discussion of Liliaceae and Amaryllidaceae, which show the fact that the idiogram type of the chromos...

L. VLASE, M. PARVU, E. A. PARVU, A. TOIU Department of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, "Iuliu Hatieganu" University of Medicine and Pharmacy, 12 Ion Creanga Street, 400010 Cluj-Napoca, Romania b Department of Biology, Faculty of Biology and Geology, „Babes-Bolyai” University, 42 Republicii Street, 400015 Cluj-Napoca, Romania c Department of Pathophysiology, ...

OBJECTIVE To examine the in vitro antibacterial activity of the ethanol extract of fresh fruits of Solanum incanum L., fresh leaves of Ricinus communis L. and Allium ampeloprasum var. porrum L., and to determine and quantify the phenol compounds of the investigated plant parts. METHODS This study was carried out at the Faculty of Science, King Khalid University, Abha, Kingdom of Saudi Arabia ...

N-nitroso compounds, such as N-nitrosodiethylamine (NDEA), can be formed by the reaction of secondary amines with nitrosating agents, and are suspected to be involved in tumors in humans. NDEA has been considered a weak carcinogen in genotoxic assays probably due to the inefficient nitrosamine activation system that is used and/or to the efficient repair system. In this work, we evaluated the s...

Hospital effluents are serious problems in developing countries like Brazil, and when not treated adequately, can cause mutagenic effects on live organisms. Biomonitors, like Allium cepa L., which is one of the most used plant species when monitoring effluent genotoxicity, have been used to alert the world population about environmental contamination and genotoxic chemical emissions. The Allium...