In this study, alkaline colloidal silica was prepared by titration of an alkaline solution such as sodium silicate with silicic acid in constant range of pH  .This constant range of pH was achieved by using concentrated soduim silicate solutions as pH adjusting solutions during titration.The sodium silicate solutions  having a variety of...

Mice were given single injections of HN2 solution at pH 8 or pH 2. The alkaline preparation had an LDM of about 2 mg/kg while that for the acidic preparation was about 5 mg/kg. A simi lar difference in toxicity was seen when the HN2 w:asgiven as a series of small daily doses. The greater toxicity of the alkaline preparation was manifest also in the hématologie findings, and in the earlier deat...