Calcium-alkali syndrome is characterized by hypercalcemia, renal injury and metabolic alkalosis. Calcium-alkali syndrome caused by calcium carbonate and vitamin D has been increasing in association with their growing use for the treatment and prevention of osteoporosis. Renal injury is the most critical factor determining the severity and prognosis of this syndrome. This review focuses on the m...

This is a case of Milk-AlKali syndrome in a patient who presented with the classical triad of hypercalcemia, metabolic alkalosis and renal impairment. The source of calcium was over-the-counter calcium-containing antacid (Tums®). Milk-alkali syndrome was first recognized secondary to treatment of peptic ulcer disease with milk and absorbable alkali. Its incidence fell after the introduction of ...

In recent years, zirconia has been a recognized implant material in clinical dentistry. In the present study, we investigated the performance of an alkali-modified ceria-stabilized tetragonal ZrO₂ polycrystalline ceramic-based nanostructured zirconia/alumina composite (NANOZR) implant by assessing surface morphology and composition, wettability, bovine serum albumin adsorption rate, rat bone ma...

purpose : to evaluate the effects of topical sesame oil in the treatment of severe corneal alkali injury in rabbits methods : in a double-blind experiment, 30 healthy white rabbits were randomized into a sesame oil treatment group (n=15) and a control group (n=15). under general anesthesia, severe corneal alkali injuries were induced by application of 1 n sodium hydroxide for 40 seconds to the ...

Staphylococcus aureus enterotoxins C1 (SEC1) and C2 (SEC2) produced from 50-liter quantities of crude culture supernatants were purified chromatographically in a neutral or acid milieu. Microheterogenity of SEC1 was markedly increased by treatment of the purified toxin with alkali, and new more acidic charged species appeared. SEC2 was more heterogenous than any of the other S. aureus enterotox...

Healing of corneal alkali injuries remains a severe clinical challenge. The authors evaluated the effect of a new synthetic inhibitor of matrix metalloproteinases (GM6001 or N-[2(R)-2-(hydroxamido carbonylmethyl)-4-methylpentanoyl]-L-tryptophane methylamide) on preventing ulceration of rabbit corneas after alkali injury. Topical treatment of corneas with severe alkali injuries with 400 microgra...

Some pulp mills expect to produce viscose fiber by means of pre-existing pulp production lines as used for conventional kraft pulp having a relatively high content of hemicellulose. In the present study oxygenreinforced alkali extraction was used to dissolve the oxidized lignin, which increased the content of alpha cellulose and increased the degree of mercerization. This paper considers the in...

Advanced additive manufacturing techniques such as electron beam melting (EBM), can produce highly porous structures that resemble the mechanical properties and structure of native bone. However, for orthopaedic applications, such as joint prostheses or bone substitution, the surface must also be bio-functionalized to promote bone growth. In the current work, EBM porous Ti6Al4V alloy was expose...

A procedure is described for the purification of a neutral protease from fermentation broths of Vibrio proteolyticus. The key feature of the purification scheme is the selective, irreversible inactivation of a contaminating exoenzyme, aminopeptidase, by alkali treatment, rather than removal of this enzyme by conventional chromatographic methods. Fermentation broths or concentrates were brought ...