نتایج جستجو برای: algd

تعداد نتایج: 85  

Background and Objective: Pseudomonas aeruginosa is one of the most important pathogenic bacteria causing infectious diseases that include resistance to many antibiotics. In addition, existence of LasIand AlgD gene contributes to pathogenicity of this bacterium. This study is aimed to investigate the frequency of mentioned genes, ‌antibiotic resistance and a significant relationship between the...

Journal: :jundishapur journal of microbiology 0
sedighe rashno taee department of medical microbiology and immunology, faculty of medicine, arak university of medical sciences, arak, ir iran behzad khansarinejad department of medical microbiology and immunology, faculty of medicine, arak university of medical sciences, arak, ir iran hamid abtahi department of medical microbiology and immunology, faculty of medicine, arak university of medical sciences, arak, ir iran mohammad najafimosleh department of microbiology, faculty of medicine, hamadan university of medical sciences, hamadan, ir iran ehsanollah ghaznavi-rad department of medical microbiology and immunology, faculty of medicine, arak university of medical sciences, arak, ir iran; molecular research center, faculty of medicine, arak university of medical sciences, arak, ir iran; department of medical microbiology, faculty of medicine, arak university of medical sciences, arak, ir iran. tel: +98-8634173526, fax: +98-8634173526

conclusions the results of the present study showed that in comparison with previously published primer sets, p. aeruginosa infection can be diagnosed with higher sensitivity and specificity by the conventional pcr assay using the newly designed primers. it was also shown that the results of the pcr assay on clinical samples of severe infections became positive much earlier than the results of ...

Journal: :Journal of bacteriology 2006
Paula Ann Kivistik Marta Putrins Külliki Püvi Heili Ilves Maia Kivisaar Rita Hõrak

As reported, the two-component system ColRS is involved in two completely different processes. It facilitates the root colonization ability of Pseudomonas fluorescens and is necessary for the Tn4652 transposition-dependent accumulation of phenol-utilizing mutants in Pseudomonas putida. To determine the role of the ColRS system in P. putida, we searched for target genes of response regulator Col...

 Background and purpose: Pseudomonas infections include urinary tract infections (UTIs), respiratory infections, soft tissue infections, dermatitis, bacteremia, gastrointestinal, bone and joint infections, and systemic types of infections, especially in hospitalized patients with severe burns, or patients with immunosuppression such as cancer or AIDS. Considering the importance of the virulence...

2012
Edward E. Pryor Elizabeth A. Waligora Binjie Xu Sheri Dellos-Nolan Daniel J. Wozniak Thomas Hollis

AmrZ, a member of the Ribbon-Helix-Helix family of DNA binding proteins, functions as both a transcriptional activator and repressor of multiple genes encoding Pseudomonas aeruginosa virulence factors. The expression of these virulence factors leads to chronic and sustained infections associated with worsening prognosis. In this study, we present the X-ray crystal structure of AmrZ in complex w...

Journal: :The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 2008
Eliana Guedes Stehling Wanderley Dias da Silveira Domingos da Silva Leite

A total of 120 strains of Pseudomonas aeruginosa, isolated from cystic fibrosis (CF) patients (n = 80) and from patients having extra-pulmonary infections (n = 40) were studied regarding the presence of some virulence factors (hemolysin, gelatinase and elastase production) and presence of the algD and algU genes as detected by polymerase chain reaction-PCR. There was not a significant differenc...

ژورنال: :تحقیقات بالینی در علوم پیراپزشکی 0
نرگس پور زرشکی دانشگاه آزاد اسلامی واحد زنجانسازمان اصلی تایید شده: دانشگاه آزاد اسلامی زنجان (islamic azad university of zanjan) تقی ناصرپور فریور مرکز تحقیقات سلولی و مولکولی ، دانشگاه علوم پزشکی قزوینسازمان اصلی تایید شده: دانشگاه علوم پزشکی قزوین (qazvin university of medical sciences) امیر پیمانی مرکز تحقیقات سلولی و مولکولی دانشگاه علوم پزشکی قزوینسازمان اصلی تایید شده: دانشگاه علوم پزشکی قزوین (qazvin university of medical sciences)

چکیده زمینه: سودموناس آئروژینوزا به عنوان یک عامل بیماریزای فرصت طلب در بیماران مبتلا به بیماری های زمینه ای می باشد که در سالهای اخیر به سبب بروز مقاومت دارویی مشکلات فراوانی را برای متخصصین کنترل عفونت ایجاد کرده است. اکثر عفونت های ناشی از این ارگانیسم توسط سویه های موکوئید ایجاد می شود که به سبب تولید اگزوپلی ساکاریدی از جنس آلژینات باعث اتصال و تشکیل بیوفیلم در بافت هدف می شود که افزایش می...

Journal: :Microbiology 2012
Aled E L Roberts Sarah E Maddocks Rose A Cooper

The presence of Pseudomonas aeruginosa in cutaneous wounds is of clinical significance and can lead to persistent infections. Manuka honey has gained ground in clinical settings due to its effective therapeutic action and broad spectrum of antibacterial activity. In this study, the effect of manuka honey on P. aeruginosa was investigated using MIC, MBC, growth kinetics, confocal microscopy, ato...

Journal: :Infection and immunity 2005
Sumita Jain Dennis E Ohman

The opportunistic pathogen Pseudomonas aeruginosa secretes a capsule-like polysaccharide called alginate that is important for evasion of host defenses, especially during chronic pulmonary disease of patients with cystic fibrosis (CF). Most proteins for alginate biosynthesis are encoded by the 12-gene algD operon. Interestingly, this operon also encodes AlgL, a lyase that degrades alginate. Mut...

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