The clinical syndrome of aspirin-intolerant asthma (AIA) is characterized by aspirin/nonsteroidal anti-inflammatory drug intolerance, bronchial asthma, and chronic rhinosinusitis with nasal polyposis. AIA reactions are evidently triggered by pharmacological effect of cyclooxygenase-1 inhibitors. Urine sampling is a non-invasive research tool for time-course measurements in clinical investigatio...

BACKGROUND AND OBJECTIVE The high-affinity IgE receptor comprises a tetramer of the ligand-binding alpha chain, a signal-augmenting beta chain, and a signal-transducing gamma chain dimer on mast cells. We hypothesized that the three subsets of the FCER1 gene may play a role in the development of the aspirin-intolerant asthma (AIA) phenotype and analyzed these genetic polymorphisms in associatio...

The aim of this research is to compare indigestible internal markers acid insoluble ash (AIA) and acid detergent lignin (ADL) and total collection of faeces (TCF) for apparent digestibility estimation in Caspian horse. Analyses were carried out on wheat straw, alfalfa, barley and maize, for dry matter (DM), organic matter (OM), crude protein (CP), ether extract (EE), neutral detergent fiber (ND...

There has been increasing evidence that genetic mechanisms contribute to the development of aspirin-intolerant asthma (AIA), a life-threatening disease. The complement component (C6) is a constituent of a biochemical cascade that has been implicated in airway epithelial damage and nasal polyposis, and therefore, may be a risk factor for AIA. To investigate the association between C6 variations ...

Aspirin-induced asthma (AIA) is a distinct clinical syndrome characterized by severe asthma exacerbations after ingestion of aspirin or other non-steroidal anti-inflammatory drugs. The exact pathomechanism of AIA remains unknown, though ongoing research has shed some light. Recently, more and more attention has been focused on the role of aspirin in the induction of oxidative stress, especially...

BACKGROUND Antithyroid drugs (ATDs) can lead to the development of agranulocytosis, which is the most serious adverse effect. Characteristics of ATD-induced agranulocytosis (AIA) have seldom been reported due to the rarity. In this study, we characterized the clinical features for AIA in Korean patients. METHODS We retrospectively reviewed data from patients with AIA diagnosed between 1997 an...

Purpose: To investigate the effect and mechanism of action of Ermiao san (EMS), a traditional Chinese herbal formula, on inflammation development and production of inflammatory mediators in adjuvantinduced arthritis (AIA). Methods: AIA was induced by injection of 0.1 ml Freund’s complete adjuvant (FCA, 10 mg/ml) in the left hind footpad of the rats. AIA rats were intragastricly treated with 0.5...

Aspirin-intolerant asthma (AIA) is a subtype of bronchial asthma characterized by development of bronchoconstriction evoked by non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs inhibit the cyclooxygenase pathway, leading to enhancement of the lipoxygenase pathway. We evaluated allelic association of 370 single nucleotide polymorphisms (SNPs) of 63 candidate genes, mostly from the arachidon...

This paper provide a review of the active integrated antenna (AIA) technologies. After a brief introduction on the definition and some historical remarks, the paper concentrates on the research effort on the past decades or so. The AIAs are reviewed in its various functions. First, an oscillator-type AIA is presented, followed by very interesting aspects of coupled oscillator arrays for phase c...

Automatic image annotation (AIA) is an active topic of research in computer vision and pattern recognition. In the last two decades, large amount of researches on AIA have been proposed, mainly including classification-based methods and probabilistic modeling methods. As one of the most common methods for AIA, support vector machine (SVM) has been widely applied in the multimedia research commu...