The Journal of Clinical Pediatric Dentistry Volume 33, Number 2/2008 155 INTRODUCTION The importance of a prompt diagnosis and treatment of periodontitis in children is emphasized by the association between the presence of periodontitis in primary dentition and periodontitis at older ages in the same individual. The 1999 International Workshop for a Classification of Periodontal Diseases and Co...

BACKGROUND There is a strong evidence that genetic as well as environmental factors affect the age of onset, severity and lifetime risk of developing periodontitis. The objective of the present study was to compare and to evaluate the association between interleukin (IL)-1α(-889) and gene polymorphisms in patients with generalized aggressive periodontitis, chronic periodontitis and healthy cont...

To determine the prevalence of aggressive periodontitis and associated systemic manifestations in Moradabad district, Uttar Pradesh, India. 3000 patients, including 1872 males and 1128 females were evaluated with mean age of 30.99. The study population was classified into three groups: gingivitis, chronic periodontitis and aggressive periodontitis. Subjects with aggressive periodontitis were fu...

Periodontitis is a highly prevalent, biofilm-mediated chronic inflammatory disease that results in the loss of the tooth-supporting tissues. It features two major clinical entities: chronic periodontitis, which is more common, and aggressive periodontitis, which usually has an early onset and a rapid progression. Natural killer (NK) cells are a distinct subgroup of lymphocytes that play a major...

Aggressive periodontitis is a rare, severe and rapidly progressing periodontal disease. Early diagnosis is of utmost importance for establishing treatment in order to stop periodontal destruction and prevent tooth loss. The aim of this study is to describe the occurrence of aggressive periodontitis in patients at a Dental School in Brazil by means of a cross-sectional study. First, records from...

There is strong evidence that genetic as well as environmental factors affect the development of periodontitis, and some suggestion that aggressive and chronic forms of the disease share the same genetic predisposition. This study addresses the hypothesis that there are both shared and unique genetic associations in these forms of periodontitis. A sample of 51 patients with aggressive disease, ...

BACKGROUND The aim of this pilot study was to test whether diagnostic agreement of aggressive and chronic periodontitis amongst Board Certified Periodontists, is influenced by knowledge of a patient's age. In 1999 at the International World Workshop age was removed as a diagnostic criteria for aggressive periodontitis. The impact of this change on the diagnostic reliability amongst clinicians h...

background: periodontal subgingival pathogens affect local and systemic immune responses and initiate an acute phase systemic inflammatory response characterized by the release of c-reactive proteins (crps). this study has been carried out to evaluate the serum concentration of crps, which can be used as a marker of periodontal disease as well as a risk indicator for cardiovascular diseases. ma...

Background and Aim: Considering the critical role of inflammatory responses in periodontal disease, knowledge about the immune system and cytokines seems nec-essary. The aim of this study was to evaluate the level of IL-23 and IL-17 in gingival crevicular fluid (GCF) of patients with chronic and aggressive periodontitis, before and after non-surgical periodontal therapy. Materials and Methods:...

Periodontitis is a multifactorial disease associated with several risk and susceptibility factors (66). Risk factors are part of the causal chain, or expose the host to the causal chain. The presence of a risk factor directly increases the probability of a disease occurring, and the absence of a risk factor reduces this possibility. Risk factors are modifiable. Contrary to modifiable risk facto...