We wished to confirm that, in patients with lung cancer, trends in demography and histology, together with modest improvements in survival, first seen in the 1976-1983 cohorts, continued to 1990. All lung cancer patients resident in Yorkshire are notified to the Cancer Registry, whose database was analysed for this report. A total of 38,275 patients were notified. There was no change in annual ...

Like other cultural variants, tastes in companion animals (pets) can shift rapidly. An analysis of American Kennel Club puppy registrations from 1946 through 2003 (N = 48,598,233 puppy registrations) identified rapid but transient large-scale increases in the popularity of specific dog breeds (fads). Nine breeds of dogs showed particularly pronounced booms and busts in popularity. On average, t...

We investigated age and performance in distance-limited ultra-marathons held from 50 km to 1,000 km. Age of peak running speed and running speed of the fastest competitors from 1969 to 2012 in 50 km, 100 km, 200 km and 1,000 km ultra-marathons were analyzed using analysis of variance and multi-level regression analyses. The ages of the ten fastest women ever were 40 ± 4 yrs (50 km), 34 ± 7 yrs ...

National mortality and hospitalization data from the Netherlands were analysed for asthma (International Classification of Diseases) (ICD 493), acute bronchi(oli)tis (ICD 466), pneumonia and influenza (ICD 480-487), and other chronic obstructive pulmonary diseases (ICD 490 + 491 + 492 + 496) in children aged 0-14 yrs for 1980-1987. No trends were seen in the mortality in age groups 0-4 yrs and ...

Childhood asthma is frequently perceived as a disease with uniform clinical pathways. This perception might be an oversimplification. The aim of the present study was to investigate the incidence and natural course of wheeze over the first 13 yrs of life and analyse the risk factors predicting wheeze at 11-13 yrs of age. The Multicentre Allergy Study, a German birth cohort, recruited 1,314 chil...

Primary ciliary dyskinesia (PCD) is a hereditary disorder of mucociliary clearance causing chronic upper and lower airways disease. We determined the number of patients with diagnosed PCD across Europe, described age at diagnosis and determined risk factors for late diagnosis. Centres treating children with PCD in Europe answered questionnaires and provided anonymous patient lists. In total, 22...

BACKGROUND Recent studies found that the athlete's age of the best ultra-marathon performance was higher than the athlete's age of the best marathon performance and it seemed that the athlete's age of peak ultra-marathon performance increased in distance-limited races with rising distance. METHODS We investigated the athlete's age of peak ultra-marathon performance in the fastest finishers in...

Primary ciliary dyskinesia (PCD) is a hereditary disorder of mucociliary clearance causing chronic upper and lower airways disease. We determined the number of patients with diagnosed PCD across Europe, described age at diagnosis and determined risk factors for late diagnosis. Centres treating children with PCD in Europe answered questionnaires and provided anonymous patient lists. In total, 22...