A 27 month old girl with congenital microvillus atrophy received two courses of SMS 201-995, a synthetic long acting analogue of native somatostatin, in an attempt to decrease profuse secretory diarrhoea. During the first trial at 13 months of age fluid and electrolytes administered by parenteral infusion were decreased as measured by water and faecal electrolyte losses. During the second trial...

BACKGROUND In 2009, the Chalk River nuclear reactor closed for repairs that led to a critical shortage of technetium-99m (Tc-99m). Several centers used thallium-201 (Tl-201) as an alternative radiotracer for myocardial perfusion imaging. Because Tl-201 is considered by many as a suboptimal radiotracer, we sought to understand the impact of using Tl-201 (during the Tc-99m shortage) on downstream...

We report on Chandra imaging observations of the Galactic Unidentified γ-ray source GEV J1809-2327, comparing the X-ray images with new VLA 1.46 GHz and 4.86 GHz maps. The X-ray images reveal a point source connected to a non-thermal X-ray/radio nebula, supporting a pulsar/wind model for the γ-ray emitter. We also detect numerous X-ray sources from the young stellar association in the adjacent ...

apy for cancer patients. The cytotoxicity of antineoplastic agents affects not only tumor cells but also rapidly proliferating normal cells, such as those of the gastrointestinal mucosa. Common complications of chemotherapy thus include stomatitis and enterocolitis. Methotrexate (MTX) is an antimetabolite drug that blocks the production of biologically active forms of folic acid. The major lesi...

Introduction Uveitis is one of the most serious manifestations of Juvenile Idiopathic Arthritis (JIA), with the potential to cause severe sight-threatening ocular complications. The first line treatment consists of topical and oral steroids with DMARDs therapy for more severe cases, including immunosuppressive and anti-TNFa agents. Abatacept (CTLA-4 immunoglobulin) is a soluble, fully human fus...

UNLABELLED Assessment of tumor viability and necrosis of non-small cell lung cancer and detection of distant metastases are important for diagnosis, staging, monitoring the response to treatment and planning long-term management. We performed scintigraphy on patients with non-small cell lung cancer to determine the utility of three tumor targeting tracers for diagnosing primary lung cancer, for...

Stainless steel-concrete composite beam has been regarded as a new application that is widely applied in offshore bridges and high-rise buildings attracting increasing interest from engineering community. The benefits brought by stainless steel, such superior corrosion fire resistance, high strength ductility well improved durability, could offer optimal sustainable solutions for infrastructure...