objective vitamin e is a major lipid-soluble antioxidant. it has been demonstrated that vitamin e supplementation has a beneficial effect against coronary heart disease (chd). this study to investigate the effects of coronary risk factors on serum vitamin e status in patients with dyslipidaemia. materials and methods this tertiary care hospital; case - control study was comprised 237 dyslipidae...

background: recently, botulinum neurotoxin (bont)-derived recombinant proteins have been suggested as potential botulism vaccines. here, with concentrating on bont type e (bont/e), we studied two of these binding domain-based recombinant proteins: a multivalent chimer protein, which is composed of bont serotypes a, b and e binding subdomains, and a monovalent recombinant protein, which contains...

this is the first report about adverse inhibitory effect of v-guard and e-guard gasoline additives against soil beneficial streptomyces. v-guard and e-guard gasoline additives are anti valve seat recession agents used in unleaded gas for old car engines in iran. they contaminate soil and groundwater by fuel leaks and spills. streptomyces are of the major contributors to the biological buffering...

Background and Objective: The majority of bacterial infections are now treatable using different classes of antibiotics. However, the world has faced a challenge called antimicrobial resistance that will diminish most antibiotics' beneficial impacts. A valuable strategy to prevent this adverse phenomenon is to increase the antibacterial effects of antibiotics using various materials as antibiot...

The aim of the present research was focused on the antibacterial, preliminary phytochemical and pharmacognostical properties of Vicoa indica (L.)DC. via in vitro approach. The aqueous and organic solvent (hexane, chloroform and methanol) extracts from the leaves of Vicoa indica (Asteraceae) were tested against Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Vibrio parahaemolyt...

Methyl indole derivative of some 6-aryl-4,5-dihydropyridazin-3(2H)-ones (3a-e) were synthesized by Mannich reaction and evaluated as anticonvulsant against MES (50mA, for 2sec), INH (250mg/kg), scPTZ (80mg/kg) and STR (3mg/kg) induced convulsion methods at 50 mg/kg dose level. All compounds 3a-e were also evaluated as antitubercular agent against M. tuberculosis H37Rv by MABA method. All compou...

Background: Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an infectious zoonotic pathogen causing human infections. These infections, in some cases, can lead to hemolytic uremic syndrome and its life-threatening complications and even death worldwide. The first intimate bacterial adhesion, intimin (I), with its own receptor translocated intimin receptor (Tir) and E. coli secreted protein...

the aim of the present research was focused on the antibacterial, preliminary phytochemical and pharmacognostical properties of vicoa indica (l.)dc. via in vitro approach. the aqueous and organic solvent (hexane, chloroform and methanol) extracts from the leaves of vicoa indica (asteraceae) were tested against escherichia coli, klebsiella pneumoniae, salmonella typhi, vibrio parahaemolyticus, v...

methyl indole derivative of some 6-aryl-4,5-dihydropyridazin-3(2h)-ones (3a-e) were synthesized by mannich reaction and evaluated as anticonvulsant against mes (50ma, for 2sec), inh (250mg/kg), scptz (80mg/kg) and str (3mg/kg) induced convulsion methods at 50 mg/kg dose level. all compounds 3a-e were also evaluated as antitubercular agent against m. tuberculosis h37rv by maba method. all compou...