BACKGROUND Exposure to environmental toxins during embryonic development may lead to epigenetic changes that influence disease risk in later life. Aflatoxin is a contaminant of staple foods in sub-Saharan Africa, is a known human liver carcinogen and has been associated with stunting in infants. METHODS We have measured aflatoxin exposure in 115 pregnant women in The Gambia and examined the D...

The pre-harvest biocontrol approach currently used includes laboratory inoculations using non-aflatoxigenic strains of Aspergillus flavus. This strategy effectively suppresses the indigenous aflatoxigenic and reduces aflatoxin accumulation in sweetcorn. current vitro study’s main objective is to determine diametric growth rates both Aflatoxin (AF)+ AF− improve understanding competitive relation...

objective: with consideration of lethal effects of aflatoxins specially b1 on human health. estimation of aflatoxin-albumin adduct, as an important marker of aflatoxin exposure, seems essential. the aim of this study is optimization of hplc-fluorescence method for measurement of this important marker in blood serum. materials and methods: in this study, blood serum of three groups of rats as a...

Production of carcinogenic aflatoxins has been reported from members of Aspergillus section Flavi, Aspergillus section Nidulantes and a newly proposed Aspergillus section Ochraceorosei that consists of Aspergillus ochraceoroseus and A. rambellii. Unlike members of section Flavi, A. ochraceoroseus and A. rambellii have been shown to accumulate both aflatoxin (AF) and the aflatoxin precursor ster...

A study was conducted on the impact of aflatoxin (AF) and mycotoxin binders on immunization against Infectious Bursal Disease (IBD) and Infectious Bronchitis (IB) in chickens. Broiler chicks (7-day-old) were randomly assigned to 9 dietary treatments with 4 replicates of 12 chicks each. Treatments were 1) control; 2) diet containing corn naturally contaminated with AF (NCD); 3) NCD + 0.2% Farmag...

Maize kernels are highly susceptible to Aspergillus spp. infection and aflatoxin (AF) contamination. Fatty acid signaling molecules appear to mediate the plant-fungal interaction by affecting the growth, development, and AF production of the fungus. In particular, fatty acid derivatives of the plant lipoxygenase (LOX) pathway are implicated in the Aspergillus spp.-seed interaction. The 9(S)-hyd...

Aflatoxin (AF) albumin adducts are found in peripheral blood after exposure to aflatoxin B, (AI-H,) and the measurement of these adducts is potentially a useful tool in the epidemiolÃ3gica!study of the role of AFBi in the etiology of liver cancer. Three complementary approaches to the quantitation of AF-albumin adducts are described: (a) enzymelinked immunosorbent assay (ELISA) performed direct...

Aflatoxin (AF) albumin adducts are found in peripheral blood after exposure to aflatoxin B1 (AFB1) and the measurement of these adducts is potentially a useful tool in the epidemiological study of the role of AFB1 in the etiology of liver cancer. Three complementary approaches to the quantitation of AF-albumin adducts are described: (a) enzyme-linked immunosorbent assay (ELISA) performed direct...

The chemical properties of β-glucans leading to their inhibition on aflatoxin (AF) production by Aspergillus flavus remain unclear. In this study, structurally modified lentinan derivatives were prepared by carboxymethylation, sulfation, and phosphorylation to explore their inhibition activity to AF synthesis. The results demonstrated that inhibitory activity of lentinan decreased at higher or ...

background: aflatoxins are toxic fungal metabolites enable to contaminate a wide range of natural substrates. this contamination can be host-specific for different plant species. in this study, the ability of a toxigenic aspergillus parasiticus to produce various aflatoxins on major iranian cereals was evaluated with special focus on plant susceptibility to toxin production at cultivar level. m...