The physicochemical characteristics and oral absorption of a poorly water-soluble drug, K-832, adsorbed onto porous silica (Sylysia 350), were compared with those of K-832 adsorbed onto non-porous silica (Aerosil 200). K-832 and silica were treated with supercritical CO(2) (scCO(2)) to produce K-832-Sylysia 350 and K-832-Aerosil 200 formulations. Scanning electron microscopy, polarizing microsc...

Abstract
 
 Background: Banyuwangi has the potential of diverse natural resources. One example plant that can be utilized is butterfly pea (Clitoria ternatea L.). The contents are phenolic acids, stilbenes (phytoalexins), flavanols, anthocyanins, flavonols and flavanones, polyphenols flavonoids. In this research, preparations were developed from extract into powder form to make it mor...

Hydrophobic grade fumed silicas are generally used in tabletting as lubricants. They are also found to retard the release of pharmaceutical actives. This is because of their hydrophobic nature, which gives good cohesive and adhesive properties. considering this point it was thought that they could be used as dry coating agents for solid dosages forms. The model drug selected for this work was p...

Breeding sturgeons in aquaculture is the only way to preserve them as a raw material for fish food products today. In this regard, not need development of commercial sturgeon breeding obvious, but also importance research aimed at studying and developing optimal modes industrial cultivation different species sturgeon. The aim work expand range compound feed sturgeons, expense unused reserves ex...

Understanding the influence of storage time on the rheological properties polymeric fumed silica gels is very important in the field of composite polymer electrolytes. A rheological study of the aging process of Aerosil R805 suspension in Polypropylene Glycol Mw2000 has been carried out by means of steady and oscillatory experiments.

Guaco (Mikania glomerata Sprengel) syrup is one of the most popular herbal medicines used to treat the symptoms of asthmatic bronchitis, cough and hoarseness. The coumarin 2H-1-benzopyran-2-one, is one of the major constituents of Guaco and contributes to its pharmacological effects. The pharmaceutical capsule form of dry extract of Guaco is recommended by the Brazilian Program of Medicinal Pla...

Liquid crystals offer many unique opportunities to study various phase transitions with continuous symmetry in the presence of quenched random disorder (QRD). The QRD arises from the presence of porous solids in the form of a random gel network. Experimental and theoretical work supports the view that for fixed (static) inclusions, quasi-long-range smectic order is destroyed for arbitrarily sma...