Abstract Background Olorofim, the first orotomide antifungal, selectively inhibits fungal dihydroorotate dehydrogenase (DHODH), a key enzyme in pyrimidine biosynthesis. Olorofim is active against Aspergillus (including azole-resistant and cryptic species), resistant moulds (e.g., Lomentospora prolificans, Scopulariopsis) dimorphic fungi Coccidioides). The drug given orally cleared by multiple C...

This paper gives an overv iew of the na tu ra l language problems addressed in the Traffic In format ion CoHator /Condenscr (TICC) p ro jeer, and describes in some deta i l the "interest ing-corner parser" used in the TICC's Na tura l Language Summariser . The TICC is designed to take free text input describing local traffic incidents, and au tomat i ca l ly ou t put local traffic in fo rmat io...

A stud y to determine whether there are any significant difTerences in perspectives of IT and business managers wit h regard to the factors which contribute to successfu l strategic ali gnment using Henderson and venkatraman's strategic ali gnment model as the research framework has been rcported .. A general survey was undertaken over a range of industrics and resu lt s indicate th at the two ...

The Effect of Experimental Methods on Science Learning Outcomes Grade V Students at SD Inpres Maroanging Gowa. Thesis. Elementary School Teacher Education Study Program, Faculty Training and Education, University Muhammadiyah Makassar. Advisor I Nasrah advisor II Nurul Magfirah. purpose this study was to determine the effect Method Class This research is a type pre-experimental with design usin...

Abstract Background CMV reactivation is occasionally detected during the work-up for hematopoietic cell transplantation (HCT) but its natural history and significance on posttransplant risk unknown. Methods seropositive 1st HCT allograft recipients in preemptive therapy era (2010-17) were analyzed. PCR testing was routinely performed before after HCT. Cumulative incidences of calculated at mult...