germline and somatic stem cells are distinct types of stem cells that are dedicated to reproduction and somatic tissue regeneration, respectively. germline stem cells (gscs), which can self-renew and generate gametes, are unique stem cells in that they are solely dedicated to transmit genetic information from generation to generation. we developed a strategy for the establishment of germline st...

Introduction: Adult stem cells are the group of cells which conserve their nature in tissues and organs among other cells. In recent years, the researchers reported the existence of stem cells on the Bulge of hair follicles near to the smooth muscle. It is possible to differentiate these stem cells to neural cells by induction of Shh, FGF, and RA factors. Because of existence of these factors ...

stem cells are self-renewing and undifferentiated cell types that can be differentiate into functional cells. stem cells can be classified into two main types based on their source of origin: embryonic and adult stem cells. stem cells also classified based on the range of differentiation potentials into totipotent, pluripotent, multipotent, and unipotent. multipotent stem cells have the ability...

trying to use embryonic stem cells about 20 years ago, working with animals,  especially rats began. during these years , many experiments in mouse embryonic stem cells to transform into a variety of cells and transplanting them were led to remarkable success . in the next issue of human stem cells were considered successful until finally in 1998 the first report was published in the proliferat...

cord blood is a rich source of hematopoietic stem cells and could be potentially used for transplantation instead of conventional sources of stem cells (bone marrow or peripheral blood). cord blood cells are successfully used in pediatric and adult patients, but their major limitation is the low number of hematopoietic stem cells for patients of large body size. there are several possible solut...

In cell therapy and regenerative medicine, a reliable source of stem cells together with cytokine growth factors and biomaterial scaffolds seem necessary. As adipose tissue is easy accessible and is abundant source of adult stem cells and can differentiate along multiple lineages, it can be considered as a good candidate in aesthetic medicine. The clinical application of adipose-derived stem ce...

introduction: adult stem cells are the group of cells which conserve their nature in tissues and organs among other cells. in recent years, the researchers reported the existence of stem cells on the bulge of hair follicles near to the smooth muscle. it is possible to differentiate these stem cells to neural cells by induction of shh, fgf, and ra factors. because of existence of these factors i...

Trying to use embryonic stem cells about 20 years ago, working with animals,  especially rats began. During these years , many experiments in mouse embryonic stem cells to transform into a variety of cells and transplanting them were led to remarkable success . In the next issue of human stem cells were considered successful until finally in 1998 the first report was published in the proliferat...

Introduction: In adult mammalian brain, neural stem cells are isolated from both the dentate gyrus and subventricular zone. This study aimed to isolate neural stem cells from adult rat subventricular zone and differentiate them into neurons and astrocytes.  Methods: In this study, the whole brain was removed after full anesthesia and creating cervical dislocation. Under a microscope, subv...