1. Aldosterone-producing adenomas were located before operation in eighteen patients by comparison of aldosterone concentrations in blood obtained by percutaneous catheterization of the adrenal vein or renal vein. The concentration of aldosterone in the venous effluent from the adrenal glands containing adenomas was significantly greater than in the venous effluent from contralateral glands. 2....

1. Adrenal tumor. (A) Abdominal computed tomography showed a large mass with smooth margin, 6.0 cm in diameter, in the left adrenal gland. No sweling of the lymph nodes around the tumor was observed. (B) An adenoma measuring 7.5×6.0×5.5 cm and weighing 122 g with a smooth surface was removed. Its cut surface was golden yelow. (C) HE stain ×20. The adenoma was encapsulated. The adjacent normal a...

To a further understanding of the role of steroid hormones in adrenal disorders, we have prepared free cell system of adrenal cells, using adrenal tissues thai had been removed by operation from (i) cases of Cushing's syndrome due to adrenocortical adenoma or adrenocortical hyperplasia, (ii) a case of primary aldosteronism, and (iii) a patient with virilizing adrenal tumor. Twelve important ste...

Lymphocytic hypophysitis represents a difficult diagnostic and therapeutic challenge. The clinical presentation of this inflammatory condition may mimic that pituitary adenoma with apoplexy. We report case 45 years old male patient acute adrenal crisis complicating chronic hypopituitarism secondary to lymphocytic hypophysitis. was managed acutely high dose steroids supportive measures, is curre...

Aldosterone-producing adenoma and bilateral adrenal hyperplasia account for >90% of all primary aldosteronism cases. Distinguishing between bilateral and unilateral disease is of fundamental importance because it allows targeted therapy. Adrenal vein sampling (AVS) is the only reliable means to preoperatively differentiate between unilateral and bilateral subtypes. A rare but serious complicati...

INTRODUCTION At times, it may be difficult to differentiate early stage, low-grade adrenocortical carcinoma from benign adrenal adenoma. CLINICAL PICTURE A 53-year-old lady underwent right adrenalectomy for a 4-cm adrenocortical tumour causing Cushing's syndrome. Histology revealed an adrenocortical adenoma. Sixteen years later, she presented with a 14-cm adrenal tumour, again on the right si...

A patient with undiagnosed pituitary insufficiency who also had a toxic thyroid adenoma is presented. The T3 secreted by the adenoma apparently corrected the secondary thyroid failure, but also aggravated the secondary adrenal failure and almost precipitated adrenal crisis. The diagnostic work-up in such an unusual co-existence is discussed, in particular since the clinical diagnosis of pituita...

A 45-yr-old woman was admitted to excise a solid hepatic tumor which was incidentally detected at ultrasound examination for an unrelated reason. Preoperative differential diagnoses included primary or secondary malignant hepatic tumors or adrenal cortical carcinoma due to aggressive imaging features. The patient underwent adrenalectomy and partial hepatectomy. The tumor proved to be an adrenal...

Pituitary adenoma is a benign neoplasm of pituitary gland. adenoma, particularly macroadenoma,may produce mass effect symptoms by compressing surrounding tissues. Due to function as aneuroendocrine organ, may also cause multiple endocrine disturbances. The authors reportthe case 39-year-old male patient presenting with chronic headache and history seizure. MRI imagingrevealed macroadenoma optic...