Background & Aims: Acute respiratory infections are common cause of mortality during childhood. This study was designed to determine the incidence of adenovirus, parainfluenza virus and respiratory syncytial virus in respiratory infections by Multiplex PCR method. Methods: This study included 168 children under 2 years of age with clinical diagnosis of bronchiolitis. Nasopharyngeal specimens we...

knowing that adenoviral vectors could initiate innate immunity, the ability of e1-deleted recombinant adenovirus (ad-e1δ) in induction of b7.1 and il-2 molecules was studied. methods: the expression of green fluorescent protein in c1498 cells following transfection of these cells with adenovirus green fluorescent protein vector confirmed the ability of adenovirus vectors in infecting the cells ...

background: the aim of the study was to determine the incidence of non-bacterial acute gastroenteritis associated with diar­rheal diseases in mazandaran province, northern iran. methods: a total of 400 symptomatic cases from patients with acute gastroenteritis from mazandaran province in iran were screened using eia method for the presence of rotavirus, adenovirus and astrovirus during 2005-200...

Background: Rotavirus infection is the most important cause of infectious, severe and dehydrating diarrhea death in children aged 5 under continues to have a significant impact on child morbidity mortality our countries. The aim this study was retrospectively determine prevalence rotavirus adenovirus patients presenting with gastroenteritis symptoms distribution pathogens according gender, age ...

background more than three million children in developing countries die from acute diarrhea annually. rotaviruses and adenoviruses are from the most important etiologic factors in acute gastroenteritis of children. objectives the aim of this study was to determine the prevalence of rotavirus and adenovirus among children with acute diarrhoea admitted to abuzar hospital in ahvaz (southwest iran)...

vaccines against the hiv-1 virus offers the best hope for eliminating hiv-associated mortality. recombinant adenovector type 5 (rad5) vaccine is a potential candidate for preventive vaccine strategies. in this study, we evaluated the rad5 prime/protein boost strategy in a murine model. we used rad5 harboring single hiv-1 genes. these genes, including gag (p24) and exon1 of tat, were amplified f...

The review article discusses vaccines against SARS-CoV 2 based on adenovirus vectors currently used in the world. concept of creating vector is described. data clinical studies efficacy and safety registered adenovirus-vector for prevention new coronavirus infection are presented. frequency serious adverse events after their use described detail. In addition, changing genotypes Covid 19 virus h...

A,t present, the laboratory confirmation of clinical adenovirus infection is generally made by either the isolation of virus in tissue culture or the finding of rising antibody tilers. Since it may take as long as two months to isolate an adenovirus and type it, and since the determination of rising titers is also laborious, it was hoped that some other method might be found for the rapid and r...

Abstract We engineered a novel adenovirus with modified capsid for use as an integrated anticancer gene therapy and to circumvent pre-existing immunity. The adenovirus, SynBAd, when administered intravenously, induced antigen-specific CD8 T cell immunity in the liver of mice (C57BL/6) splenic population effector memory cells at levels equivalent those by human Adenovirus serotype 5 (Ad5). Altho...