This paper describes methodology, toolset and case studies of adaptive planning for supply chain networks based on the holistic approach, multi-agent technology and ontological modeling. The set of tools for the development of adaptive planners can be used for a wide range of applications. Case studies are included describing applications inr adaptive airport logistics, factory planning, laundr...

Dealing with uncertainty in water resource planning is problematic because insufficient or underused infrastructure can have social and environmental costs. Multistage stochastic optimisation provides a mechanism to deal this challenge supply capacity expansion planning. However, for real systems it be mathematically hard computationally expensive. The ‘Decision-rule’ formulation represents an ...

Adaptive designs are playing an increasingly important role in the planning of clinical trials. While there exists various research on optimal determination a two-stage design, non-optimal versions still frequently applied research. In this article, we strive to motivate application adaptive and give guidance how determine them. It is demonstrated that optimizing trial design with respect parti...

Temporary flood defenses constitute a supplementary approach to permanent engineering solutions for management. However, their deployment strategy is challenge because it depends on uncertain short-term weather conditions. The strategies that later proved be insufficient or underused can have high social and environmental costs. Real options analysis (ROA) provides mechanism include flexibility...