Autoradiographic studies localize [3H]bradykinin receptor binding sites to the substantia gelatinosa, dorsal root, and a subset of small cells in both the dorsal root and trigeminal ganglia of the guinea pig. [3H]Bradykinin labeling is also observed over myocardial/coronary visceral afferent fibers. The localization of [3H]bradykinin receptors to nociceptive pathways supports a role for bradyki...

PURPOSE To report a rare case of painful trigeminal neuropathy after lateral medullary infarct and probe its underlying pathogenesis on the basis of neuroimaging and electrophysiological study. CASE REPORT A 45-year-old man presented acute onset of unsteady gait followed by paroxysmal and electric shock-like headache in the distribution of ophthalmic branch of left trigeminal nerve in 2 days....

introduction gradenigo’s syndrome consists of ophthalmoplegia, facial palsy, and facial pain due to involvement of abducens and facial nerves as well as the trigeminal ganglion. this involvement is due to infections of ipsilateral middle ear and mastoid bone. case presentation a 14-month-old girl was referred to a private clinic with chief complaint of acute and sudden-onset right ophthalmopleg...

Introduction. Trigeminal neuralgia is a fairly rare disease manifested by acute paroxysmal pain of the type electric shock in innervation zone one or more branches trigeminal nerve. usually sporadic, but familial cases have also been described. The study can help understanding causes and mechanisms development neuralgia. We present series 4 families which 2 family members generation suffered fr...

This is a rare case of amalgam allocation in an alveolar wound of an extracted third molar. During the extraction of a mandibular third molar to a 36-year-old woman, the adjacent mandibular second molar was broken. The dentist decided to put an amalgam filling to the mandibular second molar directly after the extraction and during the same appointment. The patient soon experienced an acute cont...

OBJECTIVE This study examined modulation of trigeminal pain/nociception by 2 supraspinal mechanisms: emotional controls of nociception and diffuse noxious inhibitory controls. BACKGROUND Prior research suggests emotional picture viewing (emotional controls) and tonic noxious stimuli (diffuse noxious inhibitory controls) engage supraspinal mechanisms to modulate pain and nociceptive processes....

Petrous apicitis is a rare but fatal complication of otitis media. An infection within the middle ear can extend within the temporal bone into the air cells of the petrous apex. With only the thin dura mater separating the trigeminal ganglion and the 6th cranial nerve from the bony petrous apex, they are vulnerable to inflammatory processes, resulting in deep facial pain, lateral rectus muscle ...

Eighteen patients who subsequently developed typical trigeminal neuralgia experienced a prodromal pain termed "pre-trigeminal neuralgia." These patients described their prodromal pain as a toothache or sinusitis-like pain lasting up to several hours, sometimes triggered by jaw movements or by drinking hot or cold liquids. Typical trigeminal neuralgia developed a few days to 12 years later, and ...

Out of all the cranial nerves “Trigeminal Nerve” is fifth nerve. Trigeminal nerve possesses both components i.e. mixed as well sensitive that’s why trigeminal known a The component takes up sensation from most part face and mucous membrane to central nervous system it responsible for disease which neuralgia. characteristic feature neuralgia sudden onset pain sharp lacerating, that may last few ...

Several lines of evidence suggest a major role of the trigeminovascular system in the pathogenesis of migraine. Using functional magnetic resonance imaging (fMRI), we compared brain responses during trigeminal pain processing in migraine patients with those of healthy control subjects. The main finding is that the activity of the spinal trigeminal nuclei in response to nociceptive stimulation s...