The reaction of serum samples with bromcresol green proceeds in two steps. Albumin is responsible for the faster (less than 1 min) reaction; the slower (30-min) reaction is a measure of "acute phase reactant(s)" in serum. Serum is simply mixed with bromcresol green reagent and the absorbance is measured twice, immediately and at 60 min. Albumin concentrations, determined from the absorbance at ...

In order to clarify factors affecting recurrence, we reviewed 115 renal cell carcinoma patients without distant metastasis at diagnosis (Mo) treated from January 1975 to March 1990 at Sapporo Medical College Hospital. Of these 115 patients, recurrence (metastasis) was found in 23 (20.0%). The non-recurrence rate was 70.6% after the 5-year and 56.5% after the 10-year follow up. In 22 out of 23 p...

Photodynamic therapy (PDT) inflicts tumor tissue injury that is experienced by the host as a local trauma. This provokes a strong host response with pronounced neutrophilia as one of its manifestations. Mouse FsaR fibrosarcoma model was used for investigating photodynamic therapy (PDT)-induced neutrophilia and its link to the acute phase response. Compared to normal mice, the extent of neutroph...

The aim of this study was to determine whether visceral protein levels increase under positive nitrogen balance during times of decrease in acute-phase reactant levels in patients with burn injury. This was a post hoc analysis of a prospective, interventional study approved by the local institutional review board. A total of 10 subjects between the ages of 18 and 72 with ≥ 20% total body surfac...

hemolysis in patients exhibiting a concurrent acute-phase reaction as indicated by increases in C-reactive protein. The sensitivity of haptoglobin at a cutoff of 250 mgfL, however, is somewhat less than in situations where only hemolysis is present (2). Nonetheless, it is apparent that the decline in serum haptoglobin concentrations, owing to its complexing with hemoglobin and eventual removal ...

Background: Several instances of pneumonia from an unknown cause were recorded in the city Wuhan, China December 2019, and later confirmed as coronavirus illness 2019. (COVID-19). Pneumonia is inflammatory disease that impacts parenchyma lungs, resulting consolidation afflicted area filling alveolar air gaps with exudate, cells, fibrin. Acute phase reactants (APRs) are critical early detection,...