our study evaluated the differences between early and late hemodialysis (hd) initiation in the intensive care unit (icu) according to the rifle (risk, injury, failure, loss, and end-stage renal failure) and akin (acute kidney injury network) classifications. on the assumption that early initiation of hd in critical patients according to the rifle and akin criteria decreases mortality, we retros...

conclusions a few eligible articles on seismo-nephrology were found in iran, and a limited number of current articles had poor or fair quality. as expected, the chaotic situation after mass disasters and the lack of documentation led to the loss of much important data on the diagnosis and management of victims. lessons learned from the current researches can be used as a valuable guide for futu...

background: renal ischemia reperfusion (ir), one of the most important causative mechanisms of acute kidney injury, is a major clinical problem that occurs in some hospitalized patients. the aim of this study was to investigate the effects of hydroxytyrosol (ht) on renal ischemia-reperfusion injury in mice. methods: male mice were randomly assigned to three groups (n = 9): (1) sham operated, (2...

conclusions in our study, hydroalcoholic extract of cyperus scariosus linn. offered nephroprotection in the form of aki prevention and for the treatment of established aki. results serum creatinine was significantly increased (p < 0.05) while 24 hours urine output, urine creatinine, and serum protein were significantly decreased (p < 0.05) in rats treated with gentamicin as compared to the cont...

background few studies have focused on patients’ characteristics that affects acute kidney injury (aki) after total knee replacement surgery (tkr). objectives the primary objective of this retrospective study was to identify patients’ characteristics associated with aki after tkr. patients and methods between january 2008 and december 2009, 659 patients with a mean age of 67.1 years (range, 39-...

conclusions where there is a relationship between two longitudinal and survival responses, joint modeling can estimate it. background admission to the icu (intensive care unit) is frequently complicated by early aki (acute kidney injury). the development of aki following cardiac surgery is particularly associated with increased mortality and morbidity. according to akin (acute kidney injury net...

Background: Preterm birth occurs in a large number of pregnancies, and its incidence has been reported to be on the rise. Acute kidney injury (AKI) is a common complication in the premature infants with respiratory distress syndrome (RDS). The present study aimed to determine the predictive factors, clinical courses, and outcomes of AKI in the neonates with the clinical and radiological manifes...

Objective(s):Recently cell therapy is a promising therapeutic modality for many types of disease including acute kidney injury (AKI). Due to the unique biological properties, mesenchymal stem cells (MSCs) are attractive cells in this regard. This study aims to transplant MSCs equipped with nuclear factor E2-related factor 2 (Nrf2) in rat experimental models of acute kidney and evaluate regenera...

background: acute kidney injury (aki) has been recognized as one of the most complex clinical complications in modern medicine, and ischemia/reperfusion (i/r) injury is well-known as a main reason of aki. in addition, aki leads to important systemic consequences such as acute lung injury. this study was designed to investigate the role of erythropoietin (epo) on kidney function makers and tissu...

Neonatal Acute Kidney Injury (AKI) is characterized by a sudden decline in renal function, or failure of physiologic rise glomerular filtrate rate, leading to the kidneys' inability maintain fluid and electrolyte homeostasis.1,2 Despite significant attention given epidemiology acute kidney injury adult older paediatric populations, there paucity data on neonatal AKI. There has been notable lack...