A new spectral library-based approach that is capable of screening a diverse set of finished drug products using only an active pharmaceutical ingredient spectral library is described in this paper. This approach obviates the need for a comprehensive drug product library, thereby streamlining the use of spectral library-based tests for anti-counterfeiting efforts, specifically to target finishe...

Objectives To assess variation between prescription intentions and what was actually administered to paediatric patients and the problem of converting adult dosages to paediatric doses in a ward setting. Method A prospective descriptive study was carried out at Ward 01, Lady Ridgeway Hospital, Colombo. Administration of drugs to 170 patients was directly observed and recorded during drug rounds...

To characterize the role of hen eggs used for analyzing the insect Mylabris phalerata a traditional Chinese medicine for curing liver cancer, egg white was separated from the whole egg and added to M. phalerata. The volatile compounds found in egg white when added to M. phalerata and therefore in M. phalerata itself were analyzed by GC. Cantharidin was detected both in egg white added to M. pha...

Generic and brand name antiretroviral drugs are becoming increasingly available in developing countries. We analyzed 6 antiretroviral medications from 4 international sources for drug content. The active ingredient in tested drug products was within 15% of the labeled amount (range, -12% to +15%) for drugs that were properly stored.

Strain BCT-7112, previously identified as Bacillus cereus var. toyoi, is the type strain of the species Bacillus toyonensis, a novel species of the B. cereus group. The complete genome of this strain, which is the active ingredient of the feed additive preparation Toyocerin, has been sequenced and annotated to reveal the genetic properties of this probiotic organism with a long history of safe ...

The initial soil penetration of Premise 75 and Termidor SC, containing imidacloprid and fipronil, respectively, were tested in laboratory columns of five different soils. Three combinations of application concentration and volume were used: double the recommended active ingredient concentration at one half the recommended volume (DR), the full concentration and volume (FR), and one half the con...

BACKGROUND TO THE DEBATE The UK Medical Research Council defines complex interventions as those comprising "a number of separate elements which seem essential to the proper functioning of the interventions although the 'active ingredient' of the intervention that is effective is difficult to specify." A typical example is specialist care on a stroke unit, which involves a wide range of health p...

A water-soluble chicken extract is popularly consumed as a traditional health food. The studies made revealed that it could increase the survival time and inhibit the increase of locomotor activity in rats loaded with food-deprived activity stress. The mechanism for this might be related to an elevation of the brain histamine level, and the active ingredient, carnosine, might contribute to this...