BACKGROUND/AIM Staphylococcus aureus infection associated with orthopedic implants cannot always be controlled. We used a knee prosthesis model with implant-related osteomyelitis in rats to explore induction of an effective immune response with active and passive immunization. MATERIALS AND METHODS Fifty-two Sprague-Dawley rats were divided into active (N=28) and passive immunization groups (...

OBJECTIVE To examine the effect of patient selection criteria on immunization practice assessment outcomes. METHODS In 3 high- (50%-85%) and 7 low- (<25%) Medicaid pediatric practices in urban eastern Virginia, we assessed immunization rates of children 12 and 24 months old comparing the standard criteria (charts in the active files excluding those that documented the child moved or went else...

1. Immunization of rabbits with Type III pneumococci is effective in producing active immunity against infection with a virulent strain of the homologous organism. 2. Immunization of rabbits with Type I or II pneumococci, and with R forms derived from any of the fixed types, is equally effective in producing active immunity against Type III infection. 3. Immunization of rabbits with nucleoprote...

BACKGROUND Tobacco smoking is the largest preventable cause of morbidity and premature mortality in the world. Although its medical consequences are well documented, 20-50% of the population even in developed countries remain tobacco smokers. The drugs presently used in smoking cessation have limited efficiency and, therefore, there is a need for alternative and improved treatments. One novel a...