OBJECTIVES To describe the clinicopathologic features of melanocytic proliferations associated with lichen sclerosus (LS) and to compare these findings with those in controls. DESIGN Cohort study. SETTING Academic and private practice dermatology and dermatopathology services. PATIENTS Cases of melanocytic proliferations associated with LS and consecutive controls with persistent (recurre...

OBJECTIVE To evaluate the prevalence of common acquired melanocytic nevi and its relationship with pigmentary characteristics and severe sunburns in children. DESIGN Cross-sectional study. SETTING Kaunas city, Lithuania (latitude of 55 degrees 55 minutes). PATIENTS A random sample of 484 children aged 1 to 2 years, 4 to 5 years, and 9 to 10 years and adolescents aged 14 to 15 years. INT...

Figure 1. Preoperative photograph showing the overlying melanocytic nevi. DESCRIPTION We present a 13-year-old male patient with congenital melanocytic nevi and a yearlong history of enlarging right preauricular mass. Examination revealed 2 congenital melanocytic nevi overlying a large, firm, mobile 2.7 × 2.5-cm subcutaneous mass with irregular borders. Pathology confirmed intradermal melanocyt...

"Nevi of special sites" is a term that denotes melanocytic nevi presenting in specific anatomic locations including the scalp, genital area, flexural sites, and acral sites [1]. Nevi from these anatomic sites display at times histopathologic features that may lead the reading pathologist to recommend re-excision of these benign nevi. Reflectance confocal microscopy (RCM) is a noninvasive imagin...

Studies surveying melanomas associated with melanocytic nevi in Asia are rare. In this study, we examined whether nevus-associated melanomas differ from de novo melanomas in terms of their associations with clinical factors, histologic characteristics, and patient survival in Taiwan. Using data on cancer cases obtained from the Department of Pathology archives and the Cancer Registry of Nationa...

OBJECTIVE To investigate changes in dermoscopic patterns of acquired acral melanocytic nevi (AAMN) over time. DESIGN Retrospective analysis of digital dermoscopic follow-up of 230 AAMN located on acral volar skin. SETTING Outpatient clinics at university dermatology departments. Patients A total of 230 AAMN located on the soles (n = 149), fingers (n = 62), and palms (n = 19), of 230 white s...

OBJECTIVE To investigate the dermoscopic features of acquired acral melanocytic nevi (AAMN) in a white population in Turkey. DESIGN Prospective population-based study. SETTING University dermatology department dermoscopy unit. PATIENTS A total of 2625 patients admitted to our dermoscopy unit. INTERVENTIONS Patients were examined for AAMN clinically and dermoscopically with a digital ima...

OBJECTIVE To characterize the dermoscopic features of acral congenital melanocytic nevi (CMN). DESIGN Retrospective independent evaluation of dermoscopic images by 2 dermoscopists. SETTING A dermatology clinic at a university hospital. PATIENTS Using the files of the clinic from January 1, 2004, through February 28, 2009, we selected cases with CMN lesions affecting acral volar skin that ...

BACKGROUNDS Epidemiological studies have shown a significant relationship between melanocytic nevi and cutaneous melanoma. OBJECTIVE To evaluate the development of melanocytic nevi in the pupils of a school composed primarily of children of Dutch descent and to assess the effect of environmental factors on these individuals whose phenotypic characteristics were similar to those of their ances...

OBJECTIVE To investigate the usefulness of a novel marker for melanocytic proliferations. DESIGN Using a novel monoclonal antibody against soluble adenylyl cyclase (sAC), various benign and malignant melanocytic proliferations were immunostained. SETTING Weill Medical College of Cornell University dermatopathology laboratory. MAIN OUTCOME MEASURES The results were qualitative, not quantif...