نتایج جستجو برای: acetyl groups

تعداد نتایج: 752147  

Journal: :European Journal of Organic Chemistry 2022

A mild and efficient one-pot protocol to selectively remove N-acetyl groups, subsequently functionalize the generated amines, is reported. Common functional such as esters, carbamates thioglycosides, are tolerated.

 کامران اکبرزاده, , حسین لدنی, , حمیدرضا باصری, , صغری دوستی, , منصوره شایقی, , مهدی ناطق پور, ,

Background: Although there have been many studies on the role of mosquitoes in malarial transmission, the biology and interaction of plasmodium with its host is still not completely known. The aim of this study was primarily to follow the sporogony cycle of Plasmodium vivax in Anopheles stephensi mysorensis and then to explore the inhibitory effects of certain carbohydrates on parasitic develop...

Journal: :The Biochemical journal 2005
Takhar Kasumov Jillian E Adams Fang Bian France David Katherine R Thomas Kathryn A Jobbins Paul E Minkler Charles L Hoppel Henri Brunengraber

We reported previously that a substantial fraction of the acetyl groups used to synthesize malonyl-CoA in rat heart is derived from peroxisomal beta-oxidation of long-chain and very-long-chain fatty acids. This conclusion was based on the interpretation of the 13C-labelling ratio (malonyl-CoA)/(acetyl moiety of citrate) measured in the presence of substrates that label acetyl-CoA in mitochondri...

2012
Guang Ping Cao Sundarapandian Thangapandian Shalini John Keun Woo Lee

Introduction: Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from ε-N-acetyl lysine amino acids of histone proteins. Their action is opposite to that of histone acetyltransferase that adds acetyl groups to these lysines. Only few HDAC inhibitors are approved and used as anti-cancer therapeutics. Thus, discovery of new and potential HDAC inhibitors are necessary in ...

Journal: :Organic letters 2003
Kin-ichi Oyama Tadao Kondo

[reaction: see text] 1,1,3,3-Tetramethylguanidine (TMG)(1), a nitrogen organic base, is a convenient and useful reagent for chemoselective deprotection of both silyl and acetyl groups on acidic hydroxyl groups such as phenol and carboxylic acid without affecting aliphatic silyl and acetyl groups. The chemoselectivity is dependent on the acidity of the hydroxyl group.

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